March 2021 in “Annals of palliative medicine” This meta-analysis found that plum-blossom needling, as an add-on therapy, provided moderate beneficial effects on hair regrowth in alopecia areata patients compared to conventional treatment alone.
February 2024 in “BMC genomics” This study identified a gene variant in the TRPV3 gene that may explain the suri alpaca phenotype, characterized by longer and less crimped fleece, suggesting this variant's involvement in the development of these hair characteristics compared to the huacaya phenotype.
43 citations
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November 2009 in “Archives of dermatology” This study found that alefacept showed no significant improvement in treating severe alopecia areata compared to placebo over a 24-week period.
11 citations
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October 2010 in “Behavioural Brain Research” This study found that neonatal administration of allopregnanolone enhances, while finasteride suppresses, the effects of adult intrahippocampal pregnenolone sulphate on rat locomotor activity in an open field test.
March 2025 in “Journal of Investigative Dermatology” 29 citations
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October 2009 in “Pharmacology Biochemistry and Behavior”
14 citations
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January 2017 in “Pharmacological Reports” TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
5 citations
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January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that PRP was effective for treating alopecia areata with similar improvement across groups, while topical delivery via fractional CO2 laser or microneedling reduced injection pain.
3 citations
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April 2023 in “Dermatologica Sinica” This study found that platelet-rich plasma treatment was an effective and safe option for reducing severity in patients with mild patch-type alopecia areata.
52 citations
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May 2011 in “Journal of Neuroendocrinology” This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.
16 citations
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May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
11 citations
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November 2006 in “Journal of Veterinary Diagnostic Investigation” In this case study, an 8-year-old female Huacaya alpaca displaying male behavior was diagnosed with an ovarian benign interstitial (Leydig) cell tumor, indicated by elevated testosterone levels.
18 citations
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January 2013 in “Psychoneuroendocrinology” Neonatal neurosteroid levels affect adult brain function and behavior.
July 2018 in “International Journal of Research in Medical Sciences” In this study, platelet-rich plasma treatment showed minimal effectiveness for Alopecia Areata but was more effective than no treatment, with a 20% improvement observed compared to 3.3% in the control group.
1 citations
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November 2023 in “SKIN The Journal of Cutaneous Medicine” 61 citations
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September 2011 in “Pain” This study observed that N-palmitoylethanolamine (PEA) may relieve pain by enhancing de novo neurosteroid synthesis, evidenced by increased allopregnanolone levels and protein expression in pain models, dependent on PPAR-α.
107 citations
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August 2014 in “Dermatologic Surgery” This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.
December 2024 in “Ukrainian Journal of Dermatology Venerology Cosmetology” This study observed that after 12 weeks of using the nutraceutical Alpenta, women with acute or chronic telogen effluvium experienced significant improvements in hair growth parameters, including increased anagen hair percentage, hair density, and diameter, with high patient satisfaction and good product tolerability reported.
July 2014 in “Planta Medica” This article reviews the use of Eclipta Alba, a traditional Ayurvedic herb, in liver health, hair growth, and diabetes management, but it reports no new research findings.
July 2024 in “Journal of Investigative Dermatology” The Fas/FasL pathway may play a role in alopecia areata.
July 2022 in “Media Dermato Venereologica Indonesiana” In this case study, a 29-year-old man with alopecia areata experienced satisfactory hair regrowth after five months of combined intralesional triamcinolone acetonide and platelet-rich plasma therapy.
25 citations
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January 2018 in “Acta Clinica Croatica” This study found that allogeneic platelet gel significantly improved healing in non-healing chronic lower leg ulcers compared to hydrogel treatment.
3 citations
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February 2020 in “The journal of gene medicine” This study found a recurrent nonsense mutation in the HR gene linked to atrichia with papular lesions in two Kashmiri families, suggesting whole exome sequencing as an efficient method for diagnosis and genetic counseling.
December 2023 in “International journal of research in dermatology” In this study, adding intralesional platelet rich plasma to topical mometasone proved more effective and showed earlier improvement in treating alopecia areata compared to using topical mometasone alone.
6 citations
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February 2019 in “Scientific reports” This study demonstrated that allopregnanolone administration caused significant scratching in atopic dermatitis mice, and ethanol-induced scratching may be linked to increased brain allopregnanolone levels.
14 citations
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August 2019 in “Clinical and Experimental Dermatology” This study suggests that combining microneedling with ALA-photodynamic therapy may be a promising treatment option for moderate to severe alopecia areata, achieving significant hair regrowth in some patients.
July 2026 in “Journal of the American Academy of Dermatology” December 2024 in “CONICET Digital (CONICET)” This study found that the small signaling peptide RALF22 plays a key role in root hair growth response to volatile compounds emitted by Penicillium aurantiogriseum through ethylene, auxin, and photosynthesis signaling in Arabidopsis.
January 2007 in “Журнал Гродненского государственного медицинского университета” This study found that plasmapheresis treatment in children with total alopecia led to a decrease in lead levels and improved hair growth, which was not achieved with Spirulina platentis supplements.