January 2025 in “Advancements in Life Sciences” This study found that both autogenic and allogenic PRP therapies significantly improved wound contraction and healing in rabbits by day 15 and achieved complete wound closure by day 21, outperforming control and heterogenic PRP treatments.
11 citations
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November 2011 in “Neuroreport” In this study, paroxetine's antihyperalgesic effect in a rat model of neuropathic pain was shown to be mediated by increased levels of the neurosteroid allopregnanolone in the spine.
16 citations
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September 2018 in “Journal of Molecular Liquids” This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.
17 citations
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January 2021 in “Agrobiological Records” This study reported that allethrin caused dose-dependent toxico-pathological effects, including decreased feed intake, body weight, and blood parameters, and organ damage in adult male albino rats.
January 2026 in “JPRAS Open” In this pilot study, PDLLA scalp microinjections showed improvement in physician-rated Global Aesthetic Improvement Scale scores over 12-24 weeks for 90% of patients with non-scarring alopecia, with no serious adverse events reported, although findings remain preliminary due to methodological limitations.
October 2023 in “Recima21” This review found that platelet-rich plasma treatment is effective for androgenetic alopecia, significantly increasing hair diameter in both sexes, but only improving hair density in men.
34 citations
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March 2011 in “Plastic and Reconstructive Surgery” This study found that custom alloplastic implants achieved a 95% success rate in reconstructing large cranial defects from warfare-related injuries, but frontal defects near airways and orbits showed higher infection and implant removal rates.
This study found that neonatal administration of Allopregnanolone may mitigate some behavioral effects of early maternal separation in adolescence, but also lead to similar adverse effects as the separation in adulthood.
August 2020 in “International Journal of Dermatology and Venereology” This study found that platelet-rich plasma injections improved alopecia severity scores in women with androgenetic alopecia after six months, though further research is needed to confirm these results.
46 citations
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September 2010 in “Veterinary Dermatology” This retrospective study documented various skin diseases in alpacas, reporting bacterial infections as the most common, along with other conditions described for the first time.
January 2026 in “Jurnal Akta Trimedika” In this case report, microneedling combined with PRP improved hair density and thickness in a 40-year-old man with androgenic alopecia, without side effects, suggesting it as a therapeutic option for those avoiding long-term pharmacotherapy.
10 citations
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August 2019 in “European Journal of Dermatology” This abstract provides no new clinical results; it discusses the role of surgery and interventional radiotherapy in treating cutaneous squamous cell carcinoma.
January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Platelet rich plasma may be beneficial for treating hair loss.
37 citations
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March 1998 in “Lupus” This case report describes a patient with SLE and APLS who developed basaloid follicular hamartomas, which persisted despite aggressive treatment for SLE, although hair regrowth occurred.
2 citations
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October 2022 in “Skin appendage disorders” This study found that platelet rich plasma (PRP) is a safe and effective treatment for alopecia areata, with no significant difference in efficacy between activated and non-activated PRP.
23 citations
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November 2017 in “Stem cell investigation” This study found that platelet lysate produced higher follicular regeneration in hair restoration surgeries compared to activated PRP and saline, with significant gains in both follicular unit and hair density.
The project developed and tested a method using plasma rich platelets to treat hair loss.
9 citations
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May 2019 in “Journal of dermatological treatment” This article reviews characteristics and mental health impacts of alopecia areata but provides no new clinical findings; future research is encouraged.
2 citations
,
September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
13 citations
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April 2020 in “European Journal of Dermatology” This study found that apremilast treatment did not result in sustained improvement for most patients with treatment-resistant alopecia areata, although one patient experienced significant benefit.
January 2020 in “ISP medicine” This review discusses the clinical treatment progress and future application prospects of platelet-rich plasma for androgenetic alopecia but reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found that ALRN-6924 effectively protected human hair follicles from cyclophosphamide-induced damage in an ex vivo setting, suggesting it may reduce both acute and permanent chemotherapy-induced alopecia.
3 citations
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May 2017 in “Dermatologic Surgery” PRP may help treat female hair loss, but more research needed.
8 citations
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June 2012 in “PloS one” This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study aims to evaluate the effectiveness of platelet-rich plasma as a sole treatment for alopecia areata, but it reports no new results.
2 citations
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October 2020 November 2003 in “Journal of Neurochemistry” This study suggests that the neurosteroid allopregnanolone may play a crucial role in how ethanol affects neurons related to alcohol addiction vulnerability.
This abstract provides no clinical results; it describes terms and navigation options for the JAMA network and its publications.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
42 citations
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November 2018 in “Archives of dermatological research” Apremilast was not effective in treating moderate-to-severe alopecia areata.