The Involvement of the Neurosteroid Allopregnanolone in the Antihyperalgesic Effect of Paroxetine in a Rat Model of Neuropathic Pain

    November 2011 in “ Neuroreport ”
    Takashi Kawano, Tomohiro Soga, Haidong Chi … Masataka Yokoyama
    Studysummary In this study, paroxetine's antihyperalgesic effect in a rat model of neuropathic pain was shown to be mediated by increased levels of the neurosteroid allopregnanolone in the spine.
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