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    Glossary Neurosteroids

    steroids produced in the brain that affect neuron function

    Neurosteroids, also known as neuroactive steroids, are a class of steroids synthesized in the brain and nervous system. They play a crucial role in modulating neuronal activity, influencing mood, stress response, and cognitive functions by interacting with neurotransmitter receptors such as GABA and NMDA.

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    Community 10 of 30

    1. Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction Reddit · 15 Jul 2026
    2. Finasteride, Neurosteroids, and Neuroplasticity - have you noticed cognitive shifts or have you continued growing? Community · 4 Jun 2026
    3. Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone Reddit · 24 Jul 2025
    4. What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas Reddit · 25 Jun 2024
    5. 33M: Adjusting Finasteride Dosage After Cognitive Side Effects - Seeking Advice Community · 21 Oct 2025
    6. Trying to understand finasteride side effects and post finasteride syndrome Reddit · 31 Oct 2020
    7. A warning to those thinking about using Dutasteride Reddit · 26 Apr 2020
    8. What can be the real reason of Finasteride SE ? Reddit · 10 Jul 2025
    9. After quitting min and fin I asked AI on how fix the mess I am in and it says: Reddit · 30 Jun 2025
    10. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
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    Research 10 of 439

    1. Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA<sub>A</sub>Receptor Function and Seizure Susceptibility Journal of Neuroscience · 2002 · 269 citations
    2. Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA<sub>A</sub>Receptors Journal of Neuroscience · 2011 · 248 citations
    3. Neurosteroid Synthesis-Mediated Regulation of GABA<sub>A</sub>Receptors: Relevance to the Ovarian Cycle and Stress Journal of Neuroscience · 2007 · 238 citations
    4. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004 · 180 citations
    5. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    6. Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research Journal of Neuroendocrinology · 2015 · 123 citations
    7. Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep Neuroscience · 2007 · 100 citations
    8. Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis Journal of Neuroscience · 2010 · 97 citations
    9. Production of 5α-Reduced Neurosteroids Is Developmentally Regulated and Shapes GABA<sub>A</sub>Miniature IPSCs in Lamina II of the Spinal Cord Journal of Neuroscience · 2004 · 88 citations
    10. The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches Pharmacology & Therapeutics · 2004 · 83 citations
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