Efficacy of Platelet Rich Plasma as Monotherapy in Treatment of Alopecia Areata

July 2021 in “ PARIPEX INDIAN JOURNAL OF RESEARCH ”

A. S. Rede, Virendra Vijay Saoji, Shashank Agrawal

platelet-rich plasma alopecia areata hair loss PRP injections autoimmune disease hair regrowth PRP

TLDR PRP injections significantly improve hair regrowth in alopecia areata.

The study aimed to evaluate the efficacy of platelet rich plasma (PRP) as a monotherapy for alopecia areata, an autoimmune disease causing hair loss. A total of 20 patients (10 male and 10 female) received PRP injections in hairless patches every 30 days for 4 sessions, with follow-ups every month for 6 months. The results, assessed through pre- and post-treatment photographs, indicated that PRP significantly enhanced hair regrowth, demonstrating its potential as an effective treatment for alopecia areata.

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Research cited in this study

13 / 13 results

research A Comparative Study of Treatment Modalities in Female Androgenetic Alopecia

3 citations, January 2016 in “International Journal of Research in Medical Sciences”

Using both minoxidil and platelet-rich plasma therapy together is more effective for hair growth in women than using minoxidil alone.

research Platelet-Rich Plasma Combined with Intralesional Triamcinolone Acetonide for the Treatment of Alopecia Areata: A Case Report

15 citations, November 2015 in “Journal of Dermatology and Dermatologic Surgery”

Mixing platelet-rich plasma with triamcinolone acetonide can potentially improve hair regrowth in alopecia areata patients.

research Applications of Platelet-Rich Plasma in Dermatology: A Critical Appraisal of the Literature

79 citations, October 2015 in “Journal of Dermatological Treatment”

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Platelet-Rich Plasma: Applications in Dermatology

22 citations, January 2015 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas”

Platelet-rich plasma might help with skin aging, ulcers, and hair loss, but more research is needed to prove its effectiveness and safety.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations, January 2015 in “International Journal of Trichology”

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

research Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia

74 citations, January 2015 in “Asian Journal of Transfusion Science”

Platelet-rich plasma (PRP) injections can effectively increase hair density and thickness in people with androgenic alopecia, without major side effects.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations, January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research Overview of Alopecia Areata

110 citations, December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

research Alopecia Areata: A Review

29 citations, June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery”

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

research Female Pattern Hair Loss: Causes, Diagnosis, and Treatment Options

23 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations, March 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

research Etiopathogenesis of Alopecia Areata: Why Do Our Patients Get It?

53 citations, May 2011 in “Dermatologic therapy”

Alopecia areata is a skin condition causing hair loss, and its exact cause is unknown, but it may involve biological mechanisms.

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What else is good. Besides the big 3.

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community To my fellow under 20s that are balding

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The conversation is about young men under 20 experiencing hair loss. They discuss their experiences and treatments used, including finasteride (fin) and minoxidil (min).

community Has anyone had experience with PRP causing or exasperating alopecia areata?

in General 96 upvotes 3 weeks ago

A 33-year-old female with androgenic alopecia experienced alopecia areata patches after PRP treatment. She is seeking others' experiences with PRP worsening alopecia areata.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

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The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

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