Study of the Effect of Topical Mometasone with Intralesional Platelet-Rich Plasma Versus Topical Mometasone Alone in the Treatment of Alopecia Areata

    December 2023 in “ International journal of research in dermatology ”
    Monika Kulhari, Mohammad Adil, Iti Varshney, Syed Suhail Amin
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

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    Studysummary In this study, adding intralesional platelet rich plasma to topical mometasone proved more effective and showed earlier improvement in treating alopecia areata compared to using topical mometasone alone.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This study compared the efficacy of topical mometasone with intralesional platelet-rich plasma (PRP) versus topical mometasone alone in treating alopecia areata (AA) in 100 patients. Group A received PRP injections every 3 weeks along with daily topical mometasone, while Group B received only the topical treatment. Over 20 weeks, Group A's mean SALT score decreased significantly more than Group B's (0.94±1.69 vs. 2.19±1.76). Excellent responses were observed in 12 patients from Group A and 5 from Group B. Minor side effects included pain in Group A (20%) and atrophy in Group B (2 patients). The study concluded that adding PRP to topical mometasone enhances efficacy and accelerates improvement in AA treatment.
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