Combination of Photodynamic Therapy with 5-Aminolaevulinic Acid and Microneedling in the Treatment of Alopecia Areata Resistant to Conventional Therapies: Our Experience with 41 Patients

April 2020 in “ Clinical and Experimental Dermatology ”

Caterina M. Giorgio, Graziella Babino, Stefano Caccavale, Teresa Russo, A. De Rosa, Robert R. Alfano, Elisabetta Fulgione, Giuseppe Argenziano

photodynamic therapy 5-aminolaevulinic acid microneedling alopecia areata hair regrowth PDT ALA MN AA

TLDR Combining light therapy, acid, and microneedling improves hair regrowth in stubborn hair loss cases.

The study evaluated the effectiveness of combining photodynamic therapy (PDT) with 5-aminolaevulinic acid (ALA) and microneedling (MN) in treating alopecia areata (AA) that is resistant to conventional therapies. The combination therapy provided better results in terms of hair regrowth in the treatment of moderate to severe AA. The study involved 41 patients and suggests that this combination therapy may be a promising treatment option for AA.

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