research Pregnancy Outcomes with Paternal Exposure to Finasteride, a Synthetic 5-Alpha-Reductase Inhibitor: A Case Series
Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.
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research Tumor Necrosis Factor-Alpha Inhibitor Associated Psoriasiform Alopecia
Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.
research Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors
Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
research 5-Alpha-Reductase Deficiency in a Saudi Girl
A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
research Using 5 Alpha Reductase Inhibitors Safely: What Primary Care Physicians Need to Know
5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
research 5-Alpha-Reductase Inhibitors in the Treatment of Male Androgenetic Alopecia: Clinical Experience
Low-dose dutasteride effectively and safely promotes hair growth in men with androgenetic alopecia.
research Inhibition of 5-Alpha Reductase Attenuates Cardiac Oxidative Damage in Obese and Aging Male Rats via the Enhancement of Antioxidants and the p53 Protein Suppression
Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research Risk of Estrogen-Driven Malignancies in Females on 5-Alpha Reductase Inhibitors
Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.
research Long-Term Treatment with a 5-Alpha-Reductase Inhibitor Alleviates Depression-Like Behavior in Obese Male Rats
Long-term finasteride treatment reduces depression and brain issues in obese male rats.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research How Do 5-Alpha-Reductase Inhibitors Change PSA Density in Patients on Active Surveillance?
5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.
research Sexual Dysfunction With 5-Alpha-Reductase Inhibitor Therapy for Androgenetic Alopecia: A Global Propensity Score Matched Retrospective Cohort Study
Taking medication for hair loss might cause sexual problems.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5α-Reductase Inhibitor Compounds in Tectona Grandis Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review
Some plant-based products might treat hair loss with fewer side effects than current medications.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research 5 Alpha-Reductase Inhibitory Potential of Solanum Nigrum for Alopecia Management
Solanum nigrum may help treat hair loss.
research Evaluation of Serum Level of Zinc Alpha 2 Glycoprotein in Male Patients with Androgenetic Alopecia
Men with male pattern baldness have higher blood sugar, bad cholesterol, and ZAG protein levels than healthy men.
research pH Stimulus-Responsive Hybrid Nanoparticles: A System Designed for Follicular Delivery of Brazilian Plant-Derived 5-Alpha-Reductase Enzyme Inhibitors
New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.
research Chronic Exposure of 5-Alpha Reductase Inhibitor in Young Male Rats Induces Metabolic Disturbance and Depressive-Like Behaviors
Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
research Chronic Exposure With 5-Alpha Reductase Inhibitor Ameliorates Anxiety and Depression-Like Behaviors by Reducing Systemic Oxidative Stress in D-Galactose-Induced Aging Male Rats
Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Evaluating 5 Alpha Reductase Inhibitors for the Treatment of Male Androgenic Alopecia
Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.
research Cloning, Computational Analysis and Expression Profiling of Steroid 5 Alpha-Reductase 1 (SRD5A1) Gene During Reproductive Phases and Ovatide Stimulation in Endangered Catfish, Clarias Magur
The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
research Use of 5-Alpha Reductase Inhibitors in Dermatology: A Narrative Review
5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.
research The Relative Effect of Monotherapy with 5-Alpha Reductase Inhibitors and Minoxidil for Female Pattern Hair Loss: A Network Meta-Analysis Study
Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.
research Exploring the Potential of Eclipta Alba: A Promising Approach for Hair Treatment Management Through 5-Alpha Reductase Inhibition
Eclipta alba extract could be a promising natural treatment for hair loss.
research Litigation Associated With 5-Alpha-Reductase-Inhibitor Use: A Canadian Legal Database Review
Canadian lawsuits involving 5-alpha-reductase inhibitors are related to persistent erectile dysfunction side effects, with no judgments against companies yet.
research Intralesional Methotrexate for Treatment of Alopecia Areata: Clinical Evaluation and Effect on Lesional TNF Alpha
Intralesional methotrexate effectively treats alopecia areata by reducing TNF-α levels, leading to hair regrowth.
research 5-Alpha Reductase Inhibitors Use in Prostatic Disease and Beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.