5-Alpha Reductase Inhibitors in Prostate Cancer: From Clinical Trials to Clinical Practice

January 2013 in “ European Urology ”

Behfar Ehdaie, Karim Touijer

5-alpha reductase inhibitors 5-ARIs finasteride dutasteride prostate cancer PCa primary prevention secondary prevention pathologic progression therapeutic progression placebo PSA progression biochemical failure definitive therapy relative risk reduction PSA doubling hormonal therapy biochemical recurrence Propecia Avodart PSA

Studysummary This study developed solid lipid nanoparticles for delivering a shRNA-encoding plasmid that effectively reduced 5α-reductase enzyme levels in vitro without significant cytotoxicity, suggesting potential therapeutic applications.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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