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research 5-Alpha Reductase Inhibitors in Prostate Cancer: From Clinical Trials to Clinical Practice

7 citations , January 2013 in “European Urology”

This study developed solid lipid nanoparticles for delivering a shRNA-encoding plasmid that effectively reduced 5α-reductase enzyme levels in vitro without significant cytotoxicity, suggesting potential therapeutic applications.

research Male pattern baldness and prostate cancer risk in a population-based case–control study

29 citations , March 2010 in “Cancer epidemiology”

This study found that early-onset male pattern baldness was associated with a reduced relative risk of prostate cancer.

research Five-alpha-reductase Inhibitors for prostate cancer prevention.

37 citations , April 2008 in “The Cochrane library”

This study concluded that five-alpha-reductase inhibitors may reduce prostate cancer risk but could increase the risk of high-grade prostate cancer in men regularly screened for the disease.

research Drugs affecting blood coagulation, fibrinolysis, and hemostasis

January 2009 in “Side effects of drugs annual”

This chapter reviews drugs affecting blood coagulation and details the increased hemorrhage risk associated with warfarin interactions, liver disease, heart failure, and antiphospholipid antibodies but reports no new clinical results.

research Dutasteride: A Review of its Use in the Management of Prostate Disorders

2 citations , January 2011 in “Clinical medicine insights”

The authors concluded that dutasteride is effective and generally safe for managing benign prostatic hyperplasia and may reduce prostate cancer risk.

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community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

484 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 6 months ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

community Meta analysis of minoxidil only vs 5AR inhibitors

in Research/Science 58 upvotes 1 year ago

Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.

community A tried and tested radical treatment for Hairloss in Men if you have enough self control.

6 months ago

The conversation suggests that abstaining from ejaculation for a few months may help stop or reverse hair loss by potentially increasing testosterone and reducing DHT levels. It also mentions the use of minoxidil and finasteride as effective treatments for maintaining hair after a hair transplant.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

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Hair Systems
Shreeji Cosmodent Dental Implant & Laser Hair ReductionAhmedabad, Gujarat · IN

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