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Finding functions for unknown GPCRs is hard but key for making new drugs.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.

α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

The monkey's hair loss was due to an autoimmune disease, not genetics.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Plasmalogens activate a channel in cells that may stimulate hair growth.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogen therapy can reduce skin aging but has cancer risks.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.