194 citations
,
November 2006 in “Science” This study identified a gene mutation in the LIPH gene associated with inherited hair loss and hair growth defects in certain populations, suggesting lipase H plays a role in hair development.
140 citations
,
December 2017 in “Journal of Controlled Release” This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
124 citations
,
April 2000 in “Nature biotechnology”
108 citations
,
December 2003 in “Lasers in surgery and medicine” This study found that combining near-infrared laser phototherapy with indocyanine green application may improve acne vulgaris by reducing active lesions and inflammation without side effects.
69 citations
,
January 2002 in “Journal of biomedical optics” This study found that commercially available dyes penetrate up to 1.2 mm into human skin, with Indocyanine Green binding to cell proteins and showing a shift in absorption peak.
65 citations
,
August 2016 in “Metabolic brain disease” This study found that children with autism spectrum disorder generally have lower levels of both essential and toxic trace elements in their hair compared to controls.
57 citations
,
August 2018 in “British Journal of Dermatology” This review discusses the pathogenesis and treatment of acne in transgender men on testosterone therapy and reports no new clinical results, emphasizing the need for tailored guidelines.
37 citations
,
October 2024 in “JAMA Network Open” This study found that among reproductive-age women across India, there was a high prevalence of PCOS, with phenotype C being predominant and most women exhibiting metabolic abnormalities, highlighting the importance of integrating PCOS management into national health strategies.
31 citations
,
December 2021 in “Materials” In a study using a mouse model of diabetes, chitosan-based hydrogels increased healing markers and improved wound closure and tissue repair compared to untreated wounds, but human efficacy needs further validation.
31 citations
,
April 2018 in “Plastic and Reconstructive Surgery” This review discusses the use of platelet-rich plasma for facial rejuvenation, acne scarring, and androgenic alopecia and reports positive outcomes but emphasizes the need for standardized preparation and application methods.
25 citations
,
November 2010 in “Journal of Molecular Structure” This preliminary study suggests that Raman micro-spectroscopy can help differentiate basal cell carcinoma from hair follicles in skin tissue sections, although some misclassification of hair follicles as carcinoma was observed.
22 citations
,
January 2014 in “Indian Journal of Endocrinology and Metabolism” This study found that metabolic syndrome or related metabolic issues are common among the family members of women with polycystic ovary syndrome.
19 citations
,
January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
10 citations
,
January 2019 in “Journal of the American Academy of Dermatology” This study found that transgender men using testosterone therapy had higher rates of acne and increased body hair growth, resembling male patterns more closely than those not on testosterone.
9 citations
,
March 2021 in “Hormones” This review discusses how COVID-19 may affect gonadal function and potential gender differences, but reports no clinical results; it highlights possible mechanisms and new treatment approaches from recent literature.
9 citations
,
November 2000 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study demonstrated that dyeing can enhance the absorption coefficient of hair follicle tissues for selective photodestruction within human skin and hair follicles.
7 citations
,
September 2017 in “Biomedical and Pharmacology Journal” This article discusses the early development of hair follicles with a focus on the formation of epidermal thickenings called placodes, reporting no new experimental results.
5 citations
,
September 2024 in “Journal of Clinical Medicine” This article reviews the pathophysiology of chemotherapy-induced alopecia and reports that scalp cooling can reduce hair loss by 50% in patients with early breast cancer receiving chemotherapy, without compromising survival or increasing scalp metastasis risk.
5 citations
,
November 2021 in “Plastic and Reconstructive Surgery” This article reviews the potential of using induced pluripotent stem cells for hair restoration, underscoring their promise over current surgical methods, but reports no new clinical results.
5 citations
,
May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
4 citations
,
July 2019 in “Vestnik Rossiĭskoĭ akademii meditsinskikh nauk / Rossiĭskaia akademiia meditsinskikh nauk” This study identified different non-genetic factors influencing androgenic alopecia in men with varying genetic risk, which may aid in developing more personalized treatments.
4 citations
,
February 2016 in “Clinical Pharmacology & Therapeutics” Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
3 citations
,
April 2024 in “Dentistry Journal” In this study, oral care products like foams and a spray, similar to tap water, improved salivary pH and oral clearance rates after exposure to Coca-Cola® in young adults, but no significant differences were found between these products and tap water.
3 citations
,
March 2022 in “Transgender Health” This review examines existing plastic surgery techniques for gender affirmation of the lower extremities, noting a lack of outcomes-based literature needed to establish best practices.
3 citations
,
November 2020 in “Biological Trace Element Research” This study found that patients with androgenetic alopecia had deficiencies in certain trace elements and vitamins, which were linked to distinct patterns of hair loss connected to androgen levels.
3 citations
,
December 2018 in “Meta Gene” This study applied a prediction model based on five SNPs to Russian males with male pattern hair loss, finding a significant association between the AR genomic region and high dihydrotestosterone levels in these patients.
2 citations
,
September 2017 in “Mehmet Akif Ersoy Üniversitesi Veteriner Fakültesi dergisi” This review discusses the anatomy and gene involvement in the development of animal hair follicles and reports no new experimental results; it calls for continued examination of gene roles in hair quality.
2 citations
,
October 2011 This study concluded that a compound formulation was effective in improving various clinical symptoms of dermatophytosis, including itching, scaling, and erythema, after 45 days of treatment.
2 citations
,
July 2004 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that multiple treatments combining NIR laser phototherapy with ICG significantly reduced inflammation and improved skin condition in acne without side effects.
1 citations
,
October 2024 in “JACC Case Reports” In this case report, a 53-year-old man developed recurrent pericardial effusions and pericarditis shortly after starting low-dose minoxidil, with symptoms appearing within 20 days, which is unusually rapid compared to previous reports.