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The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Different enzymes are active in different parts of developing mouse organs.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

The right amount of retinoic acid is essential for normal hair growth and development.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The method can measure vitamin B3 levels in human hair accurately.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

Retinoic acid affects male and female muscle energy use and function differently.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

Eating alfalfa sprouts every day can raise testosterone levels in middle-aged men, but broccoli sprouts don't have this effect.

Vitamin A affects hair loss and immune response in alopecia areata.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.