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The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.