July 2026 in “American Journal of Clinical Dermatology” In this study, oral JAK inhibitors were found to be significantly more effective than placebo in promoting hair regrowth among adults and adolescents with moderate-to-severe alopecia areata, although they were associated with an increased risk of adverse events.
3 citations
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March 2024 in “Journal of Dermatological Treatment” Baricitinib can lead to hair regrowth in alopecia areata but may also cause relapses.
May 2026 in “Journal of medical & health sciences review.” This study found that androgenetic alopecia is significantly more common in medical students compared to non-medical students in Peshawar, and its prevalence increases with academic progression, suggesting a possible link with stress or lifestyle factors.
1 citations
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November 2017 in “Dermatologic therapy” This article discusses Janus kinase inhibitors as a promising future treatment for alopecia areata but does not present new research findings.
42 citations
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September 2003 in “Journal of Investigative Dermatology” A missing mK6irs1 gene causes hair loss in mice.
3 citations
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January 2022 in “Russian Medical Inquiry” This review analyzes the interplay between atopic dermatitis and alopecia areata, suggesting that epidermal barrier dysfunction and genetic predispositions exacerbate both conditions through immune responses.
1 citations
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December 2017 in “Turkderm” This study investigated the factors affecting androgenetic alopecia and found no significant correlation between androgenetic alopecia and ischemia-modified albumin levels in young male subjects.
6 citations
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February 2019 in “JAAD case reports” This case report suggests acitretin as a potential treatment for pseudoainhum, following the successful resolution of the condition in a patient with palmoplantar keratoderma and congenital alopecia.
1 citations
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September 2021 in “Journal of Cosmetic Dermatology” This study found that the ACE gene I/D polymorphism may serve as a genetic susceptibility indicator for androgenetic alopecia in an Egyptian patient group.
December 2024 in “eCommons - AKU (Aga Khan University)” This study concluded that the platelet rich plasma injectable competency assessment tool (PICAT) demonstrated strong validity, internal consistency, and inter-rater reliability for evaluating dermatology residents at PNS Shifa Hospital.
76 citations
,
December 1987 in “International Journal of Dermatology” This article reviews the various skin manifestations associated with AIDS and does not report new clinical findings; the authors highlight the diverse range of dermatologic conditions seen in affected individuals.
6 citations
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May 2000 in “Pediatric Dermatology” This article discusses a case study supporting the reclassification of KID syndrome as an ectodermal dysplasia, introducing a potential treatment combination that may alleviate symptoms in affected patients.
20 citations
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December 2013 in “Clinical and Experimental Dermatology” This study found that among Korean men with AGA, drinking and smoking were associated with greater hair loss severity, while family history was linked to more severe hair loss and earlier onset.
13 citations
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June 2015 in “International Journal of Dermatology” In this study, non-obese females with early-onset androgenetic alopecia showed higher total cholesterol, LDL cholesterol, triglycerides, and atherogenic index, and lower HDL cholesterol compared to controls, suggesting an association with adverse cardiovascular risk factors.
2 citations
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May 2017 in “Journal of the American Academy of Dermatology” Tofacitinib helped a 19-year-old regrow hair after other treatments failed.
6 citations
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October 2014 in “Experimental Dermatology” This study suggests that AKR1C3 expression may influence PGD2-related pathways in skin squamous cell carcinoma and potentially be involved in androgenetic alopecia, although further investigation is needed to clarify its role.
46 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Acvr1b signaling is crucial for both hair follicle development and cycling in mice, with the genetic disruption leading to hair loss and a thickened epidermis.
November 2022 in “Journal of Investigative Dermatology” This study found that ILC1-like cells can induce alopecia areata in healthy human hair follicles, challenging the traditional belief that the disease is primarily driven by CD8+ T cells.
7 citations
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September 2019 in “Journal of Cellular Physiology” In this study, Akt2 and the oncogenic protein Tcl1 were found to be essential for early blastomere proliferation and embryo development in preimplantation mouse embryos.
August 2023 in “International journal of research in dermatology” This review suggests that oral Janus kinase inhibitors like tofacitinib, ruxolitinib, and baricitinib show promise for treating alopecia areata in adults, both in terms of efficacy and safety.
April 2016 in “Pharmaciana” This study found that a combination of liquorice and aloe vera extracts, particularly combination 1, resulted in the most optimal hair growth in rabbits over a 28-day period.
8 citations
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December 2020 in “The FASEB Journal” Blocking adenosine A2B receptor may prevent or treat hearing loss.
10 citations
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May 2017 in “Wound Repair and Regeneration” In this study, targeted overexpression of the BMP receptor ALK2 in mouse hair follicle stem cells altered follicle structure and impaired cutaneous wound healing.
17 citations
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June 2024 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that using an appropriate tool for measuring quality of life is vital, particularly as factors like severity, female sex, and eyebrow involvement may increase the psychosocial burden of alopecia areata.
August 2026 in “Dermatology and Therapy” This study conducted in the Kingdom of Saudi Arabia reported that severe alopecia areata presents significant treatment challenges due to limited therapies, leading to substantial impacts on patients' quality of life, mental health, and economic burdens.
This study reports two cases of severe alopecia areata showing seemingly permanent hair regrowth with a modified triamcinolone acetonide regimen involving epinephrine, and suggests a potential role for epinephrine in enhancing treatment efficacy.
October 2020 in “Revista médica sinergía/Revista médica sinergia” This review discusses the multifactorial nature of alopecia areata, noting its association with other autoimmune diseases, and highlights Janus kinase inhibitors as a new treatment option under investigation, but reports no clinical results.
24 citations
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January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that anabolic steroid use combined with plakoglobin deficiency caused pathological atrial electrical remodeling in young male mice, suggesting a higher risk of atrial myopathy for males with desmosomal gene variants.
April 2024 in “Medical & clinical research” This study reviews the range of both conventional and unconventional treatments for Alopecia Areata, highlighting the promise of biological therapies like JAK inhibitors, but notes more research is needed to optimize treatment effectiveness and personalization.