Alopecia Areata Treatment With Baricitinib: Different Relapse Phenotypes

    March 2024 in “ Journal of Dermatological Treatment ”
    Federica Dall’Oglio, Maria Rita Nasca, Francesco Lacarrubba, Pasquale Vitale, Giuseppe Micali
    TLDR Baricitinib can lead to hair regrowth in alopecia areata but may also cause relapses.
    This document discusses the occurrence of relapses in three patients with severe alopecia areata (AA) undergoing treatment with baricitinib, a JAK 1–2 inhibitor. Despite initial hair regrowth observed in all cases, relapses occurred either within the regrowth areas or in previously unaffected areas, indicating two different relapse phenotypes. The study emphasizes the importance of discussing potential relapses with patients during pretreatment counseling. The long-term clinical response to baricitinib in AA patients remains to be further evaluated. The study involved three female patients aged 28, 43, and 52, with no history of atopy or atopic dermatitis, and treatment was not discontinued despite relapses.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      by MagicBold in Research  865 upvotes 1 year ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Should I get transplant #4 or just shave my head?

      in Transplants  171 upvotes 1 year ago
      A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 3 years ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

      community Olumiant active ingredient Baricitinib

      in Research/Science  1 upvotes 3 years ago
      The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

    Related Research

    1 / 1 results