An Epidemiological Study of Androgenic Alopecia in 3114 Korean Patients

December 2013 in “ Clinical and Experimental Dermatology ”

In-Kwon Yeo, W. Y. Jang, Peng-Qiu Min, H. A. Cho, S. W. Cho, N. S. Hong, J. H. Kang, D. H. Ki, Hyun-Chul Kim, Yongsun Kim, Yongsun Kim, I. Y. Lee, S. H. Lee, E. S. Lim, Dong Ho Moon, Kyungwook Nam, C. K. Oho, Sung Keun Park, Kang G. Shin, Hwi Dong Yoo, Chang-Hee Hong

androgenetic alopecia AGA hair loss genetic predispositions androgenic alopecia

Studysummary This study found that among Korean men with AGA, drinking and smoking were associated with greater hair loss severity, while family history was linked to more severe hair loss and earlier onset.

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In a 2014 study involving 3114 Korean patients with androgenetic alopecia (AGA), researchers found that smoking and drinking were associated with the severity of AGA in male patients, while eating and sleeping habits were not significantly correlated with hair loss severity. Both male and female patients with a family history of AGA had more advanced hair loss and males had an earlier onset. The study suggested that environmental factors have a weaker influence on AGA compared to genetic predispositions. However, the study's hospital-based design may not fully represent the general population, indicating a need for further community-based research.

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research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

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research Family History and Risk of Hair Loss

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research Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors

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In this study, the researchers did not confirm previously reported links between AGA and smoking or benign prostatic hypertrophy, but found potential associations with alcohol consumption and lean body mass at age 21 that merit further investigation.

research Androgenetic Alopecia: Pathogenesis and Potential for Therapy

174 citations , November 2002 in “Expert Reviews in Molecular Medicine”

This review discusses the genetic factors contributing to androgenetic alopecia and highlights the potential for developing more effective therapies based on recent discoveries, but reports no new clinical results.

research Molecular Mechanisms of Androgenetic Alopecia

229 citations , August 2002 in “Experimental Gerontology”

This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.

research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women

157 citations , July 2001 in “British Journal of Dermatology”

In this study, the prevalence of androgenetic alopecia among Korean men and women was found to be lower than in caucasians, with Korean men showing more frontal hairline preservation and a higher incidence of 'female pattern' hair thinning.

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179 citations , September 1998 in “BMJ”

This article reviews the pathogenesis, genetic basis, and recent treatment breakthroughs for androgenetic alopecia but reports no new clinical findings.

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80 citations , January 1995 in “The American Journal of Medicine”

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research The Stumptailed Macaque as a Model for Androgenetic Alopecia: Effects of Topical Minoxidil Analyzed by Use of the Folliculogram

21 citations , October 1988 in “Clinics in Dermatology”

This study found that topical minoxidil induced hair regrowth in stumptailed macaques, with more significant effects observed in younger animals, while cessation led to renewed balding and retreatment restored regrowth.

research The Inheritance Of Common Baldness: To Be Or Not To Be?

203 citations , November 1984 in “Journal of the American Academy of Dermatology”

This study presents evidence suggesting that androgenetic alopecia is most likely inherited through a polygenic model, challenging the traditional view that it is caused by a simple Mendelian autosomal dominant gene.