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Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

The Rotterdam Study aims to understand various diseases in older adults.

Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Finasteride effectively treats central serous chorioretinopathy.

Low selenium levels can extend lifespan but worsen health issues.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Amla is a natural remedy with many health benefits, including antiviral and antibacterial properties.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The model and estimator can predict drug exposure in kidney transplant patients well.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.

South Asian women with PCOS experience more psychological distress and have a poorer quality of life, especially in social relationships, with hirsutism affecting them more than obesity.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

People with myotonic dystrophy type 1 tend to develop basal cell carcinoma at a younger age but not more frequently than others.

Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Laser hair reduction near the eyebrows can cause serious eye injuries even with safety measures.

The document lists various dermatology topics, treatments, and diagnostic methods.

KFSD is a rare condition causing scarring hair loss, with no effective treatment known at the time of the report.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.

Keratosis Pilaris Atrophicans causes skin scarring and might be treated with a new synthetic retinoid.

Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.

Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.