Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study's meta-analysis found that COVID-19 vaccines are effective and safe for children, with inactivated vaccines showing the highest effectiveness and causing less injection site pain compared to attenuated vaccines.

This study suggests that rapamycin, but not acarbose, can delay age-related loss of cochlear outer hair cells in UM-HET3 mice at doses that increase life span.

This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.

This study developed and validated a reliable method to measure finasteride levels in human plasma, which was successfully used to assess its pharmacokinetics after a 5 mg dose in healthy volunteers.

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

In this study, the authors reported that AtRXR3, a phosphorus-inducible DUF506 protein, modulates root hair growth under phosphorus stress by interacting with calmodulin and influencing calcium oscillations.

This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.

This article reviews how stem cell exhaustion contributes to aging, emphasizing the balance between proliferation and quiescence as crucial for long-term stem cell maintenance, but it reports no new results.

This review explored the chemical makeup and pharmacological effects of Lindera aggregata, identifying 349 components including sesquiterpenoids, flavonoids, and alkaloids, with various potential benefits demonstrated in vitro and in vivo, such as anti-inflammatory and antioxidant effects.

This article argues that the promissory discourse in the anti-ageing treatments market exploits societal anxieties about ageing, but its long-term sustainability is questionable as many promises remain undeliverable.

This study suggests that increased Wnt signaling may cause melanocyte stem cell exhaustion, leading to hair graying in aged mice by promoting excessive differentiation of melanocytes.

This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.

This article discusses various dermatological studies cited by previous authors and reports no new clinical results.

This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.

This study identified aging-related epigenetic and transcriptomic biomarkers and suggested that curcumin might target and inhibit the JUN gene, implicating potential therapeutic strategies against aging.

This review discusses the role of telomere length dynamics in hair follicle biology and reports no new clinical findings, emphasizing the need for further research in humans.

This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.

This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.

This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.

This review highlights the need for standardized reporting on fucoidan extract properties to better understand the relationships between chemical structures and bioactivities, and to improve the quality and utility of fucoidan-related data.

This study found that age-related fluctuations in hormones and endocannabinoids in male C57BL/6 mice showed specific patterns, with peak values observed around 2.7 to 3.4 months, with these patterns seen in both plasma and hair but with different magnitudes.

This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.

This study found that TGF-β2 may enhance collagen expression and spheroid formation in human dermal papilla cells, which could improve their hair inductivity and maintenance.

This study found that vascular endothelial growth factor may protect hair follicle stem cells from androgen-induced apoptosis in androgenic alopecia patients via the PI3K/Akt pathway.

This study found that among MtF transgender individuals, those with early-onset gender dysphoria exhibited differences in age at surgery, sexual orientation, and sexual activity compared to those with later-onset dysphoria.

In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.

In this study, researchers used computer-generated models to demonstrate that subtle changes in hair diameter, density, and style significantly affect perceptions of age, health, and attractiveness.

This symposium discussed why regenerative capacity varies among species and diminishes with age, exploring how these insights could inform regenerative medicine approaches, without presenting new experimental results.

This study found that young host mice rejuvenated aged hair follicles after transplantation, while aged host mice did not support hair growth from transplanted follicles.

This study reported that the IL1A 4-bp indel polymorphism is associated with a reduced risk of alopecia areata in Chinese populations, possibly through miR-122 mediated regulation of IL-1α expression.