January 2022 in “The Egyptian Journal of Hospital Medicine” This study found that combining fractional CO2 laser with 5% minoxidil was more effective than using 5% minoxidil alone for treating male androgenetic alopecia, and no serious adverse effects were identified.
35 citations
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May 2020 in “Frontiers in Pharmacology” This review provides a comprehensive overview of the mechanisms, efficacy, and adverse reactions of drugs commonly used for treating benign prostatic hyperplasia but reports no new clinical results.
10 citations
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December 2024 in “Allergy” This study found that tralokinumab effectively reduced the severity of moderate-to-severe atopic dermatitis over 28 weeks in adults, with significant improvements in clinical outcomes and biological markers, although 27.4% of patients discontinued treatment due to adverse events or ineffectiveness.
This study found that adding the Liangxue Zhituo prescription to a 5% minoxidil treatment resulted in a significantly higher improvement rate for patients with androgenic alopecia compared to minoxidil alone, with no significant adverse reactions reported.
October 2025 in “Figshare” This meta-analysis found that deuruxolitinib significantly improved hair regrowth and patient satisfaction in those with moderate to severe alopecia areata compared to placebo, though it was associated with manageable side effects such as elevated creatinine kinase levels, headaches, and acne, especially at higher doses.
September 2025 in “Journal of Cosmetic Dermatology” This study found that scalp micropigmentation was a safe and effective cosmetic solution for localized alopecia, showing significant improvement in visual density and high patient satisfaction without adverse events.
April 2025 in “Acta Dermato Venereologica” In this real-world study, JAK inhibitors like abrocitinib and tofacitinib led to substantial hair regrowth in 61% of alopecia areata patients over a median of 16 months, with 75% of non-responders achieving regrowth after switching medications; however, two serious adverse events were noted.
September 2023 in “Dermatology and Therapy” In a Belgian cohort study, nearly 90% of alopecia areata patients treated with oral baricitinib experienced hair regrowth, with more than 70% achieving a favorable SALT score, particularly in patchy cases, though some relapsed post-treatment. No serious adverse events were noted.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found a significant association between montelukast and neuropsychiatric adverse events such as suicidal ideation and depression, suggesting that the drug's interaction with specific genes may contribute to these effects.
April 2016 in “Journal of The American Academy of Dermatology” People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.
May 2011 in “MOspace Institutional Repository (University of Missouri)” In this study, finasteride 1 mg daily did not improve hair loss in normoandrogenic postmenopausal women and had a similar adverse event profile to placebo within the first year.
November 2007 in “Hospital pharmacy” This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.
68 citations
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January 2014 in “Dermatology research and practice” This review discusses the presentation and management of skin toxicity from epidermal growth factor inhibitors, highlighting a correlation between cutaneous adverse effects and tumor response, but reports no new clinical results.
18 citations
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May 2023 in “Preprints.org” This review provides an overview of caffeine's effects on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, highlighting both its potential benefits, such as neuroprotection and anti-aging, and possible adverse effects like elevated blood pressure, anemia, and migraine.
16 citations
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March 2015 in “Clinical Cancer Research” This review discusses the mechanism and side effects of smoothened inhibitors for advanced basal cell carcinoma, reporting no new clinical results and highlighting current management strategies for these adverse events.
15 citations
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September 2018 in “Dermatologic therapy” In this study, the use of two emollients significantly reduced itching severity in individuals with xerotic eczema, starting 30 minutes post-application, and improved skin moisture and lipid content over 14 days, while demonstrating good tolerance with few adverse events.
9 citations
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January 2018 in “American Journal of Men's Health” This study analyzed self-reports from discussion forums to categorize and understand adverse effects experienced by individuals using finasteride, suggesting a need for further investigation into post-finasteride syndrome.
3 citations
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August 2021 in “Journal of Cosmetic Dermatology” This study found that non-ablative Er:YAG laser treatment, alone or combined with other therapies, effectively improved hair quality and reduced AGA grade in patients, with high satisfaction reported and no adverse reactions.
December 2024 in “Journal of Cosmetic Dermatology” This study found that oral minoxidil was more likely to be associated with pericardial effusion compared to other adverse effects, with the relationship appearing dose independent.
September 2024 in “Journal of Cosmetic Dermatology” This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.
December 2023 in “International journal of research in dermatology” This study found that using 'moha: 5-in-1' hair oil for 8 weeks significantly reduced hair fall, increased hair growth rate and thickness, and decreased scalp dandruff among healthy adults with alopecia, with no adverse effects reported.
May 2024 in “Clinical, cosmetic and investigational dermatology” This case report describes an adolescent boy with congenital triangular alopecia who showed significant hair regrowth after eight months of treatment with 5% topical minoxidil, achieving full coverage of the affected area without adverse effects.
35 citations
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January 2012 in “The Journal of Sexual Medicine” This review examines various androgen deprivation therapy methods for advanced prostate cancer, highlighting benefits and potential cardiovascular and sexual adverse effects, but reports no new clinical results.
29 citations
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November 2022 in “Nature Medicine” This study identified thousands of variant-metabolite associations in the human plasma metabolome, offering insights into the genetic bases of metabolism and potential adverse drug effects.
2 citations
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September 2021 in “International Journal of Ayurvedic Medicine” In this study, most participants began using chemical hair dyes at a young age, experiencing adverse effects, but continued due to the perceived importance of hair color.
August 2025 in “International Journal of Ayurveda360” In this randomized controlled trial, the combination of Bhringaraja Taila Shiroabhyanga and Yastimadhuka Taila Nasya was found to significantly improve hair density, reduce hair fall, and decrease scalp visibility in females with Khalitya compared to Nasya alone, with no reported adverse effects.
September 2024 in “International Journal of Research and Review” This study found that Wiesbaden Dilution 30C significantly reduced hair fall in 76.66% of Telogen Effluvium patients, with 23 out of 30 experiencing notable improvement and new hair growth without adverse effects.
2 citations
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May 2023 in “Journal of Immunotherapy” In this case study, a 65-year-old male with hepatocellular carcinoma treated with the PD-1 inhibitor Sintilimab developed alopecia universalis alongside significant tumor regression and complete remission, highlighting a rare immune-related adverse event with effective anti-tumor outcomes.
32 citations
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June 2012 in “PLoS ONE” This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.
6 citations
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September 2017 in “Multiple Sclerosis and Related Disorders” This study suggests that nail loss may be a new, reversible adverse event related to teriflunomide treatment, akin to its known effects on hair loss.