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Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.

Infant skin cells may be less capable of repairing UV-induced DNA damage than adult cells.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.

The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

CD99 is highly present in certain skin cells and could help treat skin conditions.

Ovol2 is important for proper skin healing and hair growth.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Adult acne severity is influenced by stress, skin sensitivity, makeup, stopping oral contraceptives, and requires female-specific treatment guidelines.

Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.