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The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

High doses of cobalt stopped hair growth in rabbits.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

Fatp4 is crucial for healthy skin development and function.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.

WNT signaling is crucial for skin development and healing.

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

Fire needle therapy is an effective and better alternative to surgery for early-stage neck carbuncles.

Stem-cell therapy shows promise for skin conditions but needs more research.

Phospholipase A2 enzymes play key roles in skin health and disease.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.