95 citations
,
August 2022 in “JAMA Network Open” This study documented an increased health care burden due to post-COVID conditions in the 6 months following the acute phase of infection, providing vital evidence for resource planning.
18 citations
,
February 2023 in “Journal of Clinical Medicine” This study reported that neuropathic pain is prevalent in 6.7% of hospitalized COVID-19 patients during the acute phase and 34.3% of long COVID patients, highlighting the need for additional research.
13 citations
,
March 1986 in “Clinical Cardiology” This case report describes a 31-year-old woman who developed transient heart failure during the acute phase of Kawasaki disease, highlighting that it can cause myocardial dysfunction in adults.
7 citations
,
January 2025 in “Frontiers in Microbiology” In this study, researchers investigated the immunohistopathological characteristics of the skin in individuals during the acute phase of chikungunya infection, revealing CHIKV antigens and inflammatory infiltrates in various skin components and highlighting the role of cytokines/chemokines in the disease's skin manifestations.
4 citations
,
August 2023 in “Frontiers in Pediatrics” This study observed that children with multisystem inflammatory syndrome associated with COVID-19 exhibited physical intolerance and fatigue shortly after the acute phase, but significant improvements in exercise capacity, laboratory markers, and cardiac health were reported by six months post-discharge.
21 citations
,
January 2021 in “Journal of infection and chemotherapy” This study observed that male sex, diabetes mellitus, and high maximum C-reactive protein levels during the acute phase of COVID-19 were linked to elevated anti-SARS-CoV-2 antibody levels.
1 citations
,
December 2023 in “PubMed” This study on rats found that combining platelet-rich plasma with stromal vascular fraction cells helped accelerate burn wound healing by affecting inflammatory cell counts and COX-2 expression, with differing impacts observed between acute and sub-acute phases of healing.
April 2026 in “Research Square” This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.
October 2025 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” In this study, researchers found significant neuropsychiatric complications from dengue infection, such as anxiety, depression, and even mania, during acute and recovery phases, linked to inflammatory responses and potential direct viral effects on the central nervous system.
January 2024 in “Wiadomości Lekarskie” In this study, researchers analyzed the clinical phenotype and primary pathogenic links in patients who survive the acute phase of a critical illness and rely on prolonged intensive care, finding that these patients show persistent inflammation, nutritional deficiencies, and other chronic complications over time.
January 2021 in “Figshare” This chapter reviews current knowledge on long-term complications after acute COVID-19, differentiating between cardiorespiratory and extra respiratory sequelae, without presenting new clinical findings.
6 citations
,
July 2017 in “Clinics in Plastic Surgery” This article reviews the management of head and neck burns across different phases but presents no new clinical results.
1 citations
,
February 2002 in “Oncology Times” This research reports that arsenic trioxide achieved a complete remission rate of 87% in patients with relapsed acute promyelocytic leukemia, though its use involves manageable toxicities.
January 2020 in “Emergency Medicine News” This article discusses the clinical features, diagnosis, and management of acute radiation syndrome, using a case of a boy exposed to radioactive material in the desert, but reports no new research findings.
October 2006 in “Aging Health” This study found that dutasteride significantly reduces the risk of acute urinary retention and surgical intervention in men with benign prostatic enlargement compared to placebo.
45 citations
,
January 2008 in “Drugs” This study found that dutasteride effectively improved urinary symptoms, reduced acute urinary retention risk, and decreased prostate volume in men with moderate to severe BPH over two years.
3 citations
,
January 2016 in “Journal of Clinical & Cellular Immunology” In this study, increased production of CXCL10 was associated with the infiltration of Th1 and Tc1 cells in acute alopecia areata, suggesting a possible new target for treatment.
February 2024 in “BMJ Open” This study at Luigi Sacco University Hospital identified three key macro symptoms of long COVID—neurological, sensorial, and physical—and found that their development is associated with comorbidities, medications during acute COVID-19, and demographic factors like age and gender.
2 citations
,
May 2023 in “Experimental dermatology” In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.
3 citations
,
February 2023 in “Journal of Infection and Public Health” More symptoms during initial COVID infection increase the risk of long-term effects.
151 citations
,
May 2021 in “Frontiers in Medicine” This systematic review observed that a significant number of COVID-19 patients report long-term symptoms, including neurologic complaints and chronic fatigue, highlighting the presence of "post-COVID syndrome.
August 2025 in “IntechOpen eBooks” Long COVID affects many survivors with ongoing symptoms, needing more research and care.
September 2022 in “Research, Society and Development” This review covers the common symptoms and management considerations for Post-COVID-19 Syndrome but reports no new clinical results; the authors emphasize the need for ongoing research and updated protocols.
July 2022 in “British Journal of Dermatology” This study found that epidermal growth factor receptor inhibitors used in cancer treatment induce a distinct inflammatory response in hair follicles, marked by immune privilege collapse and upregulation of inflammatory pathways.
July 2025 in “International Journal of Trichology” This review discusses telogen effluvium, emphasizing its identifiable causes and treatment options, and reports no new clinical results.
1 citations
,
January 2024 in “Microorganisms” This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.
April 2024 in “Public health” In this study of non-hospitalized patients in Dubai, pre-COVID vaccination and treatments with favipiravir or sotrovimab were associated with a reduced risk of developing long COVID.
34 citations
,
March 2001 in “Cleveland Clinic Journal of Medicine” This article reviews the triggers, diagnosis, and management of telogen effluvium in men and women, emphasizing the role of patient education and reassurance, but presents no new clinical findings.
This case report chronicles a three-year journey of long COVID in a previously healthy 26-year-old, detailing treatment trials and near-total remission, but provides no new generalizable data.
This study found that the loss of papillary fibroblasts in the skin due to UV radiation is mainly caused by an uncontrolled inflammatory response, with T cells helping fibroblast survival.