SARS-CoV-2 Infection Reduces the Number of Spermatogonial Stem Cells and Dysregulates the Transcriptional Landscape of the Human Testis
April 2026
in “
Research Square
”
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.
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