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This review explores how colloidal drug delivery systems can enhance the stability, absorption, and bioavailability of phytochemicals, potentially rediscovering ancient compounds' therapeutic benefits and overcoming limitations like poor solubility and bioavailability.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

This review discusses the potential benefits of activating NRF2 for treating hair follicle disorders linked to oxidative stress and reports no new clinical results.

This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.

This study suggests that combining baricitinib with narrowband UV-B therapy is an effective and well-tolerated approach for treating active nonsegmental vitiligo.

This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.

This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.

This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.

This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.

This study found that nanoemulsions incorporating skin penetration enhancers significantly increased the permeation of minoxidil through human skin compared to aqueous control solutions.

In this study, the researchers reported that chloramphenicol-loaded liposomes, particularly those incorporating deoxycholic acid, enhanced follicular uptake and showed strong antibacterial activity against methicillin-resistant Staphylococcus aureus, offering potential for treating MRSA-infected skin conditions with good skin biocompatibility and minimal toxicity.

This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.

In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.

This study developed a sensitive and precise scFv-based ELISA for miroestrol quantification, aiding quality control in P. candollei plant materials and health supplements.

This article reviews advanced strategies for enhancing drug delivery to cutaneous stem cells to improve treatment for skin conditions and reports no new experimental findings.

This study found that Sol/ASC-DP nanoparticles could enhance the skin permeability of minoxidil due to improved stability and hydrophobic interactions in the nanoparticle structure.

This study concluded that chitosan nanoparticles loaded with minoxidil effectively target hair follicles and reduce dermal exposure compared to iontophoresis, despite similar drug delivery potential to the follicles.

This study found that mechlorethamine restored hair growth in mice with alopecia-areata-like disease by eliminating infiltrated lymphocytes and inhibiting certain pro-inflammatory cytokines in treated skin areas.

This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.

In this study on testosterone-induced benign prostatic hyperplasia in rats, hydroxychloroquine significantly reduced prostate-related markers and enhanced therapeutic effects when combined with finasteride, suggesting potential as a new treatment approach.

This study found that Si extract, cryptomeridiol, and SiAgNPs have the ability to induce cell death and prevent cell growth in HepG2 liver cancer cells, suggesting cryptomeridiol's potential as a phytochemical component in developing new therapies for hepatocellular carcinoma using nanotechnology in vitro.

In this study, researchers observed that Cuscuta reflexa extract mitigated inflammation and oxidative stress in testosterone-induced benign prostatic hypertrophy in Wistar rats, suggesting its potential as an adjunctive therapy for BPH.

This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.

This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.

In this study, researchers found that crude extracts from Avicennia marina and its component avicequinone C inhibit mechanisms contributing to androgenic alopecia in vitro, including 5α-reductase activity and DHT-AR interactions, potentially promoting hair growth and delaying the catagen phase in human dermal papilla cells.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

In this phase I study, partial hair regrowth was observed in patients with alopecia universalis using topical JAK inhibitors, though more research is needed to confirm potential as a treatment alternative to clobetasol.

This study found that microencapsulation combined with iontophoresis can significantly enhance the delivery of minoxidil sulphate to hair follicles, suggesting a synergetic approach for topical drug targeting.

This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.

In this study, a topical lotion containing Redensyl and Sepicontrol A5 demonstrated effectiveness for treating androgenetic alopecia over 24 weeks, with 73.1% of users seeing moderate improvement and notable increases in hair cycle ratios, alongside enhanced quality of life and satisfaction.