research Androgen Biosynthesis Inhibitors And Androgen Receptor Antagonists
Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.
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research Pharmacologic Treatment of Polycystic Ovary Syndrome
The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
research Cutaneous Toxicities From Transplantation-Related Medications
Skin problems from transplant drugs are common and need careful management in organ transplant patients.
research Spironolactone in Dermatology
Spironolactone is useful for treating acne and other skin conditions like excessive hair growth and certain types of hair loss.
research Bicalutamide and the New Perspectives for Female Pattern Hair Loss Treatment: What Dermatologists Should Know
Bicalutamide, a drug with a good safety profile, is a promising new treatment for female pattern hair loss.
research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
research High-Performance Liquid Chromatographic Determination of the Enantiomers of the Benzoquinolinone LY 191704, a Human Type 1 5α-Reductase Inhibitor, in Plasma
Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
research Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Intradermal and Follicular Delivery of Adapalene Liposomes
Liposomal adapalene improves delivery to hair follicles and reduces side effects for acne treatment.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Spironolactone May Cause Hormonally Associated Vestibulodynia and Female Genital Arousal Disorder
Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.
research Reply to Finasteride and Dutasteride May Reduce Melanoma Risk
Finasteride and dutasteride may lower melanoma risk, with teenage acne possibly indicating higher risk.
research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity
Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
research Flutamide-Loaded Zein Nanocapsule Hydrogel: A Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Tolerance of Spironolactone in Acne and Hirsutism Treatment
Most patients tolerated spironolactone for acne and hirsutism despite common side effects like menstrual changes and breast tenderness.
research Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome
Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Nanoemulgel: For Promising Topical and Systemic Delivery
Nanoemulgel is a better way to deliver drugs through the skin for various conditions.
research Uses of Spironolactone as an Antiandrogenic Drug
Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.
research Spironolactone in Dermatology: A Mini Review
Spironolactone may be effective for acne and other skin conditions and could be used more in treatment.
research Anti-Androgens: Their Use in Dermatology
Cyproterone acetate with ethynyl estradiol significantly improved acne and seborrhea in women, but was less effective for hair loss and excessive hair growth.
research Effects of Long-Term Treatment With Finasteride (MK-906), a 5-Alpha Reductase Inhibitor, on Circulating LH, FSH, Prolactin, and Estradiol
Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
research Lipid Nanoparticles for Topical and Transdermal Delivery of Pharmaceuticals and Cosmeceuticals
Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and Across the Skin
Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.
research Nanoemulgel as an Innovative Platform for Phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research Formulation, Development and Evaluation of Invasomes Loaded Clotrimazole Gel for Fungal Treatment
Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.
research Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles
Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.
research Analysis of Prescribing Practices in the Dermatology Outpatient Department of a Tertiary Care Teaching Hospital
The conclusion is that dermatologists need to improve prescription practices to reduce errors and drug interaction risks.
research Finding Models for Skin Diseases: Successes and Failures
The document concludes that while finding animal models for the skin disease Hidradenitis suppurativa is challenging, certain mouse mutations may provide useful insights for research and drug testing.