6 citations
,
January 2021 in “Annals of Dermatology” This study found that 650-nm red light treatment promoted hair follicle proliferation and delayed the transition from anagen to catagen in ex vivo hair follicles from androgenetic alopecia patients, with RNA-seq analysis suggesting involvement of biological processes like metabolism and leukocyte migration.
25 citations
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October 2022 in “Ophthalmic Research” In this study, 650 nm low-level red light therapy may cause a short-term transient increase in retinal fovea perfusion density in children, with no lasting effects observed at 1 hour post-treatment.
4 citations
,
October 2009 in “Skin research and technology” This study found that tristimulus colorimetry is a sensitive and quantitative method for projecting hair growth rates in depilated mice, and it observed that 890 nm LED irradiation promotes hair regrowth.
April 2021 in “JOJ dermatology & cosmetics” This study found that a combination treatment of laser photobiomodulation and plasma jet therapy was effective in improving alopecia areata in a 38-year-old woman after 14 sessions over three months, as evidenced by comparative photo documentation.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
February 2010 in “Journal of The American Academy of Dermatology” This study found that NB-002 demonstrated clear antifungal activity and clinically significant nail clearing in subjects with distal subungual onychomycosis and ≤50% nail involvement, compared to a vehicle treatment.
January 2024 in “Photodiagnosis and Photodynamic Therapy” The study found that combining a 655nm low-level laser helmet with 2% minoxidil resulted in better improvement in hair diameter and intermediate hair enlargement at the midscalp among Chinese women with FPHL.
2 citations
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December 2024 in “Apple Academic Press eBooks” This study reports that optimal follicular penetration in nanocarrier-assisted drug delivery for skin diseases occurs with carrier sizes between 300 and 650 nm, while certain traditional medicine practices have shown effectiveness in treating skin conditions.
33 citations
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March 2017 in “Dermatologic Surgery” In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.
April 2026 in “Biosensors” In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.
December 2025 in “Journal of lasers in medical sciences” This randomized controlled trial reported that light-emitting diode therapy significantly reduced ecchymosis and edema and accelerated wound healing in patients during the first two weeks following rhinoplasty, without any adverse effects.
8 citations
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November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
21 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.
December 2023 in “Trials” In this randomized controlled trial involving breast cancer patients undergoing chemotherapy, this study investigated the efficacy of low-level light therapy for preventing hair loss, measuring outcomes like hair count and patient quality of life, but the abstract does not report specific results.
March 2026 in “Health Science Reports” Among individuals with skin types II and III, this study found the 755 nm laser more effective for axillary hair removal than the dual-wavelength laser, with a better safety profile and enduring results up to 12 months.
February 2020 in “Journal of Physics Conference Series” This study found that laser hair removal is optimal for light to moderate skin tones using 10-15 J/cm² at 755 nm and for dark skin with 4.5-10 J/cm² at 755-1064 nm.
9 citations
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April 2019 in “Dermatologic Therapy” This study reviewed the effectiveness of long pulse 1,064-nm Nd:YAG laser treatments for leg veins, hair removal, and skin rejuvenation, highlighting its safety, particularly for darker skin types, due to reduced pigmentary side effect risks.
This study found that 1064 nm QS Nd:YAG laser treatment effectively lightens hair and improves skin appearance in Indian subjects with minimal adverse effects, offering a safer alternative to chemical lightening products.
1 citations
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November 2023 in “Clinical, cosmetic and investigational dermatology” In this review, researchers examined the current status and advancements in using long-pulse alexandrite lasers for treating hair removal, vascular lesions, and pigmented lesions, aiming to guide clinical use based on how the laser's 755nm wavelength is absorbed by melanin and hemoglobin.
1 citations
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August 2019 in “Journal of Dentistry Indonesia” This ex vivo study reported that a 645-nm wavelength red-light laser can penetrate and reach cells in the various layers of swine oral mucosa and periosteum tissue samples.
5 citations
,
October 2020 in “Lasers in Medical Science” This study found that combination therapy with LLLT and 5% minoxidil improved hair diameter and density more effectively than each treatment alone in women with female pattern hair loss.
January 2012 in “Human health handbooks” This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.
1 citations
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February 2025 in “Photodermatology Photoimmunology & Photomedicine” This study found that 830 nm LED light effectively treated post-inflammatory erythema and hyperpigmentation, while both 830 nm and 590 nm LEDs prevented post-inflammatory erythema.
106 citations
,
April 2013 in “Dermatologic Surgery” This study found that low-level light therapy significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, suggesting it could be an effective treatment option.
2 citations
,
December 2024 in “Microscopy Research and Technique” This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.
12 citations
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January 2021 in “Dermatology Research and Practice” This study found that using a nonablative 1927 nm wavelength laser followed by hydroquinone cream is safe and effective for treating postinflammatory hyperpigmentation in patients with dark skin types.
September 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a new high-power, 810 nm diode laser for hair removal, finding it to be effective and safe, with a mean hair reduction of 74.4% in one session, and noted it worked efficiently on both large and small areas with minimal side effects.
4 citations
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June 2025 in “Journal of Cosmetic Dermatology” This study found that a high-power triple-wavelength diode laser effectively and safely treated facial hirsutism and follicular disorders in individuals with darker skin tones, showing significant hair reduction without adverse events.
90 citations
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January 2009 in “Journal of cosmetic and laser therapy” In this study, low-level laser therapy showed no statistically significant improvements in hair growth measures, despite some patients experiencing increases in terminal hairs and shaft diameter.
37 citations
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January 2023 in “Ophthalmology and Therapy” In this study, more than 25% of children experienced axial length shortening greater than 0.05 mm/year following repeated low-level red-light therapy.