Immediate Effect in the Retina and Choroid After 650 nm Low-Level Red Light Therapy in Children

The study investigated the immediate effects of 650 nm low-level red light therapy (LLRLT) on the retina and choroid in 25 children, focusing on its potential to control myopia. It found that LLRLT caused a significant but temporary increase in retinal foveal perfusion density (RFPD) 5 minutes after treatment, which returned to baseline after 1 hour. No significant changes were observed in retinal fovea thickness, choroidal fovea blood flow, or choroidal fovea thickness. These findings suggested that while LLRLT may cause short-term changes in RFPD, it did not significantly affect other retinal or choroidal parameters, providing theoretical support for its potential role in myopia control. However, the small sample size of 25 subjects limited the strength of the conclusions.