4 citations,
August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
3 citations,
April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
10 citations,
January 2019 in “in Vivo” Finasteride boosts stem cell signals for hair growth.
11 citations,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
4 citations,
January 2018 in “General Physiology and Biophysics” The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
3 citations,
January 2017 in “Journal of cosmetology & trichology” The nutritional supplement improved hair quality and reduced hair loss.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
13 citations,
July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
January 2024 in “La Ciencia al Servicio de la Salud y Nutrición” Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
15 citations,
February 2018 in “Journal of Cosmetic and Laser Therapy” Laser-assisted drug delivery improves hair loss.
13 citations,
January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
7 citations,
January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
1 citations,
June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride use may cause sexual dysfunction; more research needed.
17 citations,
February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
25 citations,
June 2017 in “Scientific reports” Stress worsens Tourette symptoms by increasing allopregnanolone levels.
1 citations,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
June 2022 in “Journal of Dermatology Research” Using 448-kHz Capacitive-Resistive Electrothermal Therapy can help increase hair density and prevent hair loss in women.
12 citations,
August 2000 in “Fertility and Sterility” Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
35 citations,
February 2012 in “Journal of The American Academy of Dermatology” Finasteride significantly improves hair growth but may cause sexual side effects.
11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
66 citations,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
26 citations,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
April 2022 in “Diabetes Therapy” Low testosterone does not prevent prostate cancer in men with type 1 diabetes.
7 citations,
June 2020 in “Translational Andrology and Urology” Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
3 citations,
August 2016 in “Behavioural Brain Research” Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.
April 1998 in “Journal of women's health” Hair loss in women is often due to hereditary conditions or stress, and while treatments like minoxidil can help, diagnosis and management require medical guidance.
11 citations,
January 2006 in “Analytica Chimica Acta” Validated method reliably measures finasteride in tablets using liquid chromatography.
January 2006 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.
35 citations,
June 2012 in “Journal of Clinical Psychopharmacology” Finasteride reduces gambling symptoms in Parkinson's patients.