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Skin and nail problems like hair loss, dry skin, and fungal infections are common in people with long-term Type 2 Diabetes and can be prevented with good blood sugar control and foot care.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Finasteride side effects in young men may be linked to specific gene variations.

New compounds may help treat prostate cancer by reducing cell growth.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Certain drugs that block specific enzymes can help treat prostate diseases.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Glioblastoma cells can make androgens, which might help the tumor grow.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Hair restoration surgery techniques have evolved, with focus on patient selection and realistic goals, and future advancements may include cloning and gene therapy.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Testosterone's muscle-building effects do not require its conversion to DHT.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.