Polyglandular Syndrome Type 1 Complicated with Dilated Cardiomyopathy: A Case Report

    S. Abidi, Faizan Rasheed, Ravinder Reddy, Reshmi Francis Vadakkan, Afrasayab Khan, Navya Pillikunte Doddereddy, A Quadri, Salma Younas
    Image of study
    TLDR A 27-year-old with APS-1 showed improvement in symptoms after treatment.
    This case report discusses a 27-year-old male with autoimmune polyglandular syndrome type 1 (APS-1), presenting with fever, dysarthria, dysphagia, oral candidiasis, nail dystrophy, and alopecia since age 7. He was later diagnosed with hypoparathyroidism and dilated cardiomyopathy. Laboratory results showed hypocalcemia, hyperphosphatemia, and low PTH levels, confirming APS-1. A brain CT scan revealed bilateral symmetrical calcifications. Treatment included oral calcium, antifungal suspension, and medications for cardiomyopathy. The patient's dysphagia and dysarthria improved after treating candidiasis. This case highlights the varied manifestations of APS-1.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 4 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community 29M alopecia or normal hair fall but something worked. Just wanted to share.

      in Update  3 upvotes 1 month ago
      A 29-year-old male experienced hair loss and found improvement using a combination of onion hair oil, castor oil, ketoconazole shampoo, and aloe vera gel with vitamin E, while discontinuing minoxidil and finasteride due to side effects. He emphasizes the importance of scalp massage and oiling for hair growth and reduced hair fall.

      community mbp alopecia areata or vitamin deficiency

      in Chat 1 year ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 1 year ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

    Similar Research

    5 / 1000+ results