Autoimmune Polyglandular Syndrome Type 2 Presentation With Alopecia Universalis, Hashimoto's Disease, and Addison's Disease

    Karla Denisse Sales-Morales, Nazhira Torres-Neme, Vladimir Barrera-Villanueva, Alejandro Martínez-Carreón
    Image of study
    TLDR Timely diagnosis and treatment of complex autoimmune diseases like APS2 are crucial to prevent complications and improve life quality.
    This case report details a 30-year-old male with autoimmune polyglandular syndrome type 2 (APS2), presenting with alopecia universalis, Hashimoto’s disease, and Addison’s disease. APS2 is rare and involves primary adrenal insufficiency with autoimmune thyroid disease and/or type 1 diabetes. The case highlights the complexity of autoimmune diseases and the necessity of a multidisciplinary approach for effective diagnosis and management. It stresses the importance of timely recognition and treatment to prevent severe complications and improve quality of life, while also recommending ongoing monitoring for future comorbidities. The report notes the rarity of APS2's association with alopecia universalis, with only two other cases documented.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 1 year ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community Losing hair everywhere, idk what to do :(

       29 upvotes 6 years ago
      A 22-year-old male has been experiencing widespread hair loss for over four years, including pain and significant shedding. Treatments tried include ketoconazole shampoo, fluocinonide topical solution, biotin, ACV, and dry shampoo, but none have been effective.

      community AGA evaluation and first steps - BEGINNER MEGAPOST

      in Chat  79 upvotes 9 months ago
      The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hair loss.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 10 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

    Related Research

    6 / 6 results