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GlossaryAdrenal Insufficiency (Addison's disease)

occurs when adrenal glands produce insufficient cortisol and aldosterone

Adrenal Insufficiency, also known as adrenal failure or adrenal hypofunction, is a condition where the adrenal glands do not produce enough of certain hormones, particularly cortisol and sometimes aldosterone. This can lead to symptoms such as fatigue, muscle weakness, weight loss, low blood pressure, and skin changes. It can be caused by autoimmune disorders, infections, or other underlying health issues, and requires medical diagnosis and management.

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research Mono-Letter Mnemonics in Dermatology

December 2006 in “International Journal of Dermatology”

Mnemonics with one letter are useful and easy to remember for learning dermatology.

research Novel and Recurrent Mutations in the AIRE Gene of Autoimmune Polyendocrinopathy Syndrome Type 1 (APS1) Patients

26 citations, September 2009 in “Clinical genetics”

Arab APS1 patients have unique and recurrent AIRE gene mutations.

research Origin, Clinical Presentation, and Diagnosis of Facial Hypermelanoses

35 citations, July 2007 in “Dermatologic clinics”

Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.

research The Skin and Subcutaneous Tissues: Conditions, Diagnosis, and Systemic Implications

1 citations, January 2013 in “Springer eBooks”

The document concludes that skin and nail changes can indicate various underlying health conditions.

research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients

31 citations, May 2021 in “Journal of endocrinological investigation”

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.