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P-3074 effectively blocks scalp DHT better than oral finasteride.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.

This study examined 4-azasteroids using 13C-NMR spectroscopy, detailing the NMR spectrum assignments and reporting a new molecular complex of finasteride with dioxane.

This study examined the effectiveness of FT-Raman spectroscopy for detecting polymorphism in Lamivudine and Finasteride, highlighting its advantages over other methods due to its capability to provide sharp, well-resolved spectral bands and reduced sampling issues.

This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.

This study's model suggests that low androgen levels can increase selection for prostate cancer phenotypes resistant to hormonal therapy, potentially leading to more aggressive forms of cancer.

This study found that dual 5α-reductase inhibitors in rats decreased sperm quality and led to reduced pregnancy success, suggesting potential for use in male contraception.

This study found no statistically significant differences in extracellular water and cardiac measurements between COVID-19 patients in intensive care and those on the ward, though the NICaS device might aid fluid management.

This study identified a new FAK isoform, FAKΔe4, which is regulated by ECM stiffness and affects cell migration, invasion, and mechanosensing in human-derived data and engineered models.

This study found that transcription factors HOXC13, LEF1, and FOXN1 repress DSG4 transcription, with the Notch pathway possibly involved in maintaining DSG4 expression in hair follicles.

This study reports that PADI4, an enzyme involved in posttranslational protein modifications, regulates progenitor cell transitions in hair follicle development by repressing transcription and interacting with translational and ribosomal processes.

This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.

OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.

This paper discusses a structure-based analysis to find new BRD4 inhibitors, identifying finasteride and amentoflavone as promising candidates for BET inhibition.

This study reports the crystal structure of C28H32O5, revealing its monoclinic symmetry, unit-cell dimensions, and molecular conformation.

This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.

In this study, Dodatek A operationalizes the Functional Androgen Axis framework by defining three system-level indices and an efficiency metric to describe androgen function, incorporating key methodological improvements and acknowledging significant limitations for future empirical validation.

This study demonstrated that a combination of four types of honey significantly improved hair integrity, porosity, and surface roughness after exposure to UV-A and pollution stress.

This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.

This study found that estetrol (E4) significantly prolonged the anagen phase and increased hair matrix keratinocyte proliferation in cultured human hair follicles, suggesting its potential as a treatment for female pattern hair loss.

In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.

This study found that overexpression and knockdown of DKK4 influence genes involved in hair follicle growth and development in Angora rabbits and identified specific SNPs in DKK4 associated with wool quality, notably showing that the TT/GG haplotype combination relates to higher fibre diameters.

This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.

This paper reflects on the challenges and progress in hair restoration, highlighting ongoing efforts for improvement but providing no new empirical findings.

This study found that mutations in the FGF5 gene are the primary genetic factor causing long hair in domestic cats through an autosomal recessive mechanism.

This review summarizes existing evidence on the efficacy and safety of JAK inhibitors for treating alopecia areata and emphasizes the need for improved topical formulations.

This narrative review discusses expert consensus on the optimal use of botulinum toxin injections for cosmetic applications in facial and oral-maxillofacial areas across Asian and Caucasian populations, highlighting injection techniques, effective doses, historical context, and potential complications.

This review assesses the effectiveness of various alopecia areata treatments and concludes that only contact sensitizers like diphenylcyclopropenone and squaric acid dibutylester have shown efficacy in evidence-based studies, but it reports no new clinical results.

In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.