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The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride remains stable for two years with proper storage.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

New, cheaper method measures finasteride in tablets accurately and quickly.

Method measures finasteride in plasma, suitable for pharmacokinetic studies.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

New method accurately measures finasteride in tablets and bulk.

Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Both drugs lower DHT levels, with GI198745 being more effective.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Certain drugs that block specific enzymes can help treat prostate diseases.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Method detects finasteride in plasma and semen with high sensitivity and accuracy.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Finasteride may help some women with hair loss, but better options exist.

Finasteride temporarily lowers male rat fertility without affecting libido.

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.

Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.

Finasteride cream helps hair growth with less side effects.