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Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Certain drugs that block specific enzymes can help treat prostate diseases.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.