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The vitamin D receptor can work without its usual activating molecule.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Vitamin D is important for bones, hair, blood pressure, and breast development.