Vitamin D-Dependent Rickets Type II
July 2023
in “
Journal of medical and health studies
”
![Image of study](/images/research/fc43fac7-61cd-478c-8d32-02ff0ea75c4e/medium/29922.jpg)
TLDR A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.
The document details a case study of a 3-year-old with vitamin D-dependent rickets type II (VDDR type II), a condition marked by resistance to vitamin D and severe alopecia. Despite high-dose vitamin D and calcium treatment, the patient's health declined, leading to multiple hospitalizations and respiratory failure. Symptoms included alopecia, fragile bones, and leg bowing, with lab results showing hypocalcemia, elevated serum 1,25-dihydroxyvitamin D, and secondary hyperparathyroidism. Oral calcium therapy led to some radiographic improvement after 3.5 months, but the patient died from a severe chest infection and related complications at age 3. The case underscores the need for better understanding and management of VDDR type II.