Vitamin D-Dependent Rickets Type II

July 2023 in “ Journal of medical and health studies ”

Sharaf Al Shurafi, Lena Abu Aker, Ahmed Alfarra, Abdalkarin Rdwan, Hadeel Abu Rizq

vitamin D-dependent rickets type II VDDR type II alopecia vitamin D calcium treatment hypocalcemia 1,25-dihydroxyvitamin D secondary hyperparathyroidism oral calcium therapy calcium

TLDR A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.

The document details a case study of a 3-year-old with vitamin D-dependent rickets type II (VDDR type II), a condition marked by resistance to vitamin D and severe alopecia. Despite high-dose vitamin D and calcium treatment, the patient's health declined, leading to multiple hospitalizations and respiratory failure. Symptoms included alopecia, fragile bones, and leg bowing, with lab results showing hypocalcemia, elevated serum 1,25-dihydroxyvitamin D, and secondary hyperparathyroidism. Oral calcium therapy led to some radiographic improvement after 3.5 months, but the patient died from a severe chest infection and related complications at age 3. The case underscores the need for better understanding and management of VDDR type II.

View this study on al-kindipublisher.com →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Vitamin D-Dependent Rickets Type II with Alopecia: A Rare Case Report

11 citations, January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)”

A 4-year-old boy with a rare type of rickets and hair loss improved in bone health but not hair growth after vitamin D and calcium treatment.

research Rickets with Alopecia Signals Vitamin D Dependent Rickets Type II

1 citations, January 2016 in “Journal of Nepal Paediatric Society”

A child with rickets and hair loss might have a rare type of rickets that doesn't improve much with usual vitamin D and calcium treatment.

research Presence of a Deletion Mutation (c.716delA) in the Ligand Binding Domain of the Vitamin D Receptor in an Indian Patient with Vitamin D-Dependent Rickets Type II

18 citations, November 2009 in “Calcified tissue international”

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

research Type II Vitamin D Dependent Rickets: A Case Report

5 citations, January 1970 in “Journal of Nepal Paediatric Society”

Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.

research Rickets with Alopecia: Remission Following a Course of 1-Alpha-Hydroxy Vitamin D3 Therapy

6 citations, August 1989 in “European journal of pediatrics”

Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.

Vitamin D-Dependent Rickets Type II

Related Community Posts Join

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

community Some Motivation for You All | Fin + Min Daily since early 2022

community Guys. Your hairloss and your mental health issues connected to your hairloss are two separate issues that require two separate treatments

community Can low level of vitamins cause hair loss?

community My Vitamin D (25-0H) levels came <4.20 ng/ml (<20 implies deficiency)and B12 came 184 pg/ml (Should be between 211-911). I have a lot of dandruff. The derm has prescribed me with 60k vitamin d tablet once a week and multivitamins for a month. Vitamin deficiency implies TE no? or is it MPB?