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    Glossary Period Circadian Regulator 2

    protein regulating the body's internal 24-hour circadian rhythm

    Period Circadian Regulator 2 (PER2) is a protein that plays a crucial role in regulating the body's internal clock, or circadian rhythm. This protein helps control the timing of various physiological processes, such as sleep-wake cycles, hormone release, and metabolism, by interacting with other circadian proteins to maintain a roughly 24-hour cycle.

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      community Why I Take 5mg Minoxidil at Night Instead of Splitting 2.5mg

       9 upvotes 4 months ago
      Taking 5mg oral minoxidil at night instead of splitting 2.5mg doses, with the rationale that a single larger dose may provide a stronger activation for hair follicles and reduce peak-related side effects. Some users report sleep issues with nighttime dosing, while others find it beneficial; opinions on effectiveness and side effects vary.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

       89 upvotes 8 months ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

      community Does Creatine Really Increase DHT? My Personal Experiment

       115 upvotes 1 year ago
      Creatine does not increase DHT levels, but some report hair loss when using it, possibly due to other factors. The effects on hair loss vary individually, with no clear connection established.

      community 6 months into Dutasteride and my hair is way worse than before

      in Finasteride/Dutasteride  70 upvotes 2 years ago
      After six months on Dutasteride, the user's hair is worse than before, despite previously trying finasteride and RU/Fluridil without success. Some suggest continuing Dutasteride and adding progress photos, while others share their positive experiences or advise sticking to one treatment for at least a year.

      community My Theory Of Androgenic Alopecia

       16 upvotes 10 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
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