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GlossaryPeriod Circadian Regulator 2

protein regulating the body's internal 24-hour circadian rhythm

Period Circadian Regulator 2 (PER2) is a protein that plays a crucial role in regulating the body's internal clock, or circadian rhythm. This protein helps control the timing of various physiological processes, such as sleep-wake cycles, hormone release, and metabolism, by interacting with other circadian proteins to maintain a roughly 24-hour cycle.

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community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community How to reduce cortisol (stress hormone) naturally?

in Chat 36 upvotes 2 years ago

The conversation discusses natural ways to reduce cortisol, such as avoiding caffeine, getting proper sleep, syncing with the sun, walking in nature, breathing exercises, increasing calories, and not doing keto. Magnesium supplements are recommended for stress reduction.

community 6 months into Dutasteride and my hair is way worse than before

in Finasteride/Dutasteride 76 upvotes 7 months ago

After six months on Dutasteride, the user's hair is worse than before, despite previously trying finasteride and RU/Fluridil without success. Some suggest continuing Dutasteride and adding progress photos, while others share their positive experiences or advise sticking to one treatment for at least a year.

community 3 months. Dut, Min, Keto, Vitamin D, exercise

in Progress Pictures 353 upvotes 2 years ago

A user's experience using dutasteride, minoxidil, ketoconazole, vitamin D, scalp massage, exercise, and avoiding vaping and 2-in-1 shampoo/conditioner to treat hair loss; they also discussed the side effects of finasteride.

community Anyone had low ferritin and seen an improvement after iron supplements?

in Chat 6 upvotes 3 months ago

A user with low ferritin and zinc levels is asking if others have seen hair improvement after taking iron supplements. They were prescribed minoxidil and finasteride by their doctor.

community Glad that many influencers are coming out on taking fin and sharing their regrowth regime.

in Finasteride/Dutasteride 116 upvotes 1 year ago

The conversation is about influencers sharing their hair growth regime, specifically mentioning the use of finasteride (Fin) and minoxidil (Min). Some users express skepticism about the effectiveness of these treatments and discuss other factors that could contribute to hair loss.

community Big regrowth after a big shedding period (11 months on fin)

in Progress Pictures 104 upvotes 1 year ago

The post discusses a 21-year-old male's significant hair regrowth after experiencing shedding periods during an 11-month treatment with finasteride, minoxidil, ketoconazole, biotin, and dermaroller. The conversation encourages persistence with the treatment despite shedding phases, as hair tends to grow back thicker and longer.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 89 upvotes 3 months ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.

community Imo everyone should take serrapeptase for a short extended period to break up scar tissue in their scalp

in Research/Science 1 year ago

Treatments for hair loss, such as Minoxidil, Finasteride and RU58841, as well as using serrapeptase to break up scar tissue in the scalp.

community Progress: From June 2022 (7 months of min + fin) to now (1 year) — I’ve lost so much density in this period and I have no idea why. I was getting pretty good resultup until that point. Is there anything else I can try? I’ve tried min, fin, tretinoin, micro needling, and castor oil. I feel hopeless.

in Progress Pictures 10 upvotes 1 year ago

The user lost hair density after 7 months of using minoxidil and finasteride and is seeking advice on other treatments after trying tretinoin, microneedling, and castor oil. Suggestions include checking for scalp conditions like eczema or psoriasis, changing minoxidil brands, and questioning hair dryer use and finasteride dosage.

community Is this sign of regrowth been using fin. 1mg daily for last 7 months having massive shed since mid 6th month period ,not properly stabilized yet , should I continue.

in Is this regrowth? 6 upvotes 1 year ago

User is experiencing hair shedding after 7 months of using finasteride 1mg daily and asks if they should continue. Their routine includes finasteride, topical minoxidil, dermarolling, and vitamins like biotin and B12.

community (26M) My 3 months progress on hair loss treatment. Extremely happy with the results. I have included so many details about my stack, my experience during the treatment, progress pictures, and everything I did during this time period.

in Progress Pictures 27 upvotes 1 year ago

A user's 3-month progress report on their treatment of hair loss using a stack of finasteride, dutasteride, and minoxidil, with additional supplements, diet and workout routine, and before-and-after photos.

community Discussion: Evidence Refuting the "24-Hour Rule" for Minoxidil and Dermarolling

in Treatment 9 upvotes 4 years ago

The 24-hour waiting period after dermarolling before applying minoxidil is unnecessary. New research supports the simultaneous application of minoxidil with microneedling for better hair growth results.

community Still shedding like this everyday 9 months straight on fin and min. Should I switch to dut?

in Finasteride/Dutasteride 54 upvotes 2 years ago

A user reporting an extended shedding period of 9 months while using finasteride and minoxidil, and other users offering advice on treatments such as dutasteride, multivitamin, biotin, rosemary oil, Kiel's magic elixir, hair extensions, changing hair color, healing crystals, and seeing a dermatologist.

community How long is topical Fin “active” on the scalp?

in Finasteride/Dutasteride 6 upvotes 11 months ago

Topical finasteride remains active on the scalp for a certain period after application, and there is concern about the safety of touching the hair and transferring the medication to the fingers.

community (UPDATE) 1y and 4m progress. 1mg fin daily, minoxidil foam twice a day, keto shampoo every other hair wash and hims thick fix shampoo and conditioner. Added saw palmetto, biotin + keratin and dermarolling into my routine. super happy, so glad hair loss isn’t consuming my life anymore

in Progress Pictures 40 upvotes 1 year ago

The individual has seen hair regrowth over a period of 1 year and 4 months using 1mg finasteride daily, minoxidil foam twice daily, ketoconazole shampoo, thick fix shampoo and conditioner, saw palmetto, biotin, keratin, and dermarolling. They are pleased with the results and no longer feel overwhelmed by hair loss.

community 2.5 months result after using minoxidil+finasteride on scalp

in Progress Pictures 183 upvotes 1 year ago

And minoxidil. This user posted progress pictures after using a combination of minoxidil and finasteride over a 2.5 month period, which received various comments from other users with differing opinions.

community Almost two years on topical fin and min (and sometimes microneedling). Consistency is key

in Progress Pictures 2 years ago

Using topical fin and minoxidil (as well as potentially microneedling) for hair loss over a two year period, with the user reporting great progress. Additional questions were asked about dosage amounts, haircuts and side effects of these treatments.

community Brutal shed at 5 months

in Minoxidil 8 upvotes 3 years ago

User experienced significant hair regrowth with multiple treatments, but then had a brutal shedding period, losing progress. Others questioned the number of treatments used and potential side effects.

community Give finasteride time to work!

in Progress Pictures 296 upvotes 5 months ago

A user shared their 2-year experience with finasteride for hair loss, noting initial success, a period of shedding, and eventual improvement. Another user mentioned seeing no improvement until 14 months in, emphasizing the need for patience.

community Microneedling Minoxidil Finasteride (3 Month Report)

in Is this regrowth? 27 upvotes 6 months ago

The conversation discusses hair regrowth using microneedling, Minoxidil, and Finasteride over a three-month period. Specific treatments mentioned are microneedling, Minoxidil (Min), and Finasteride (Fin).

community Am I in a long second shed from treatment or is this my regular hair loss

in Treatment 5 upvotes 8 months ago

The user has been using Minoxidil, Ketoconazole shampoo, and a dermastamp for 7 months and experienced a period with no shedding, but is now shedding about 100 hairs a day and is questioning if this is a result of the treatment or their normal hair loss. They are unable to start finasteride and are considering stopping the treatment due to the shedding.

community For those of you using hair drugs, how long did you use them before progress peaked/stopped?

in Chat 7 upvotes 8 months ago

The conversation is about someone using minoxidil, finasteride, RU58841, and microneedling for hair loss treatment for nearly two years with ongoing improvement. They are questioning the likelihood of continued hair regrowth over a four-year period.

community My conclusive research on Hairline and most other facets of appearance

in Research/Science 10 months ago

The user emphasizes hydration, androgen receptors, and a 7-day ejaculation recovery period for appearance enhancement. They suggest Minoxidil, finasteride, and RU58841 for hair loss, along with a diet rich in animal fats, specific exercises, and fasting.

community M22 1 year 4 months topical min + oral fin

in Finasteride/Dutasteride 216 upvotes 1 year ago

A user's experience with hair loss treatments, specifically Minoxidil (topical) and Finasteride (oral), over a period of 1 year and 4 months. The user reported best results after 6 months, a significant hair shed 4 months ago, and current regrowth, while also using a 1.25mm dermastamp. The user adjusted Finasteride dosage over time and experienced high testosterone and nipple sensitivity.

community Using Minoxidil without Finasteride

in Minoxidil 1 year ago

The effectiveness of using minoxidil alone as a hair loss treatment, and whether or not finasteride should be taken in addition to the minoxidil. Replies suggest that minoxidil is only effective for a short period of time, and finasteride should be added to the treatment plan.

community Can i go for a full recovery? 6 months fin 7 months min

in Progress Pictures 1 year ago

Treating hair loss with finasteride, minoxidil, RU58841, and Nizoral, and the progress of this treatment over a period of six months.

community Kintor Pharma Announces Completion of Subject Enrollment in Phase III Clinical Trial of KX-826 for Treatment of Male Androgenetic Alopecia

in Research/Science 83 upvotes 1 year ago

Kintor Pharma completed enrolling subjects for a Phase III trial of KX-826 for male hair loss treatment. The trial includes a 24-week treatment period and a 4-week safety follow-up, with results expected in about 6-7 months.

community Check out this shed-topical finasteride/topical minoxidil

in Progress Pictures 253 upvotes 2 years ago

This conversation is about a user who has been using topical finasteride and minoxidil to treat their hair loss, with the result being an intense shedding period. Other users have offered advice and encouragement for them to keep going with the treatment, suggesting they may see significant regrowth in 6 months time.

community Finasteride two years results from horrible shed

in Progress Pictures 2 years ago

This user experienced severe hair loss, but was able to successfully treat it with finasteride over a two year period. Despite experiencing multiple shedding cycles while on the medication, Mission5896 reported that their hair continued to get thicker and stronger. Additionally, they tried both minoxidil orally and topically, but only found success with finasteride.