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Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Testosterone may slow down wound healing and increase inflammation.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

New tests detect finasteride and dutasteride in urine quickly and easily.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Sebocytes play a key role in controlling androgen levels in human skin.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Both mouse and rat models are effective for testing alopecia areata treatments.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

DHT, a testosterone byproduct, causes male pattern baldness.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.