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This study found that incorporating steroid hormones into DPPC liposomes altered their physicochemical properties, including size, zeta potential, and phase transition temperatures.

This study found a high prevalence of clinical signs and functional disorders of androgen excess in premenopausal women, with idiopathic hyperandrogenism and idiopathic hirsutism rates similar to PCOS.

This study suggests that the role of vitamin 25(OH)D in the pathogenesis of PCOS and diminished ovarian reserve may be independent of serum vitamin 25(OH)D levels.

This review discusses the roles of prostaglandins in hair loss and highlights their potential as targets for new alopecia treatments, but reports no new clinical findings.

Blocking a protein called prostaglandin D2 might help treat hair loss.

PGD2 stops hair growth and is higher in bald men with AGA.

This study found that a low-dose intermittent finasteride regimen significantly reduced hirsutism scores in adolescent girls with PCOS or idiopathic hirsutism, with similar efficacy but potentially safer and less expensive than continuous administration.

This study found that total testosterone, DHEA-S, and free androgen index may help distinguish menstrual irregularities from increased risk of polycystic ovary syndrome in adolescents.

This study reported that the topical treatment HDMHG0401-10 significantly improved hair density in men with androgenetic alopecia compared to placebo, although subjective hair growth ratings were not significantly different.

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

In this study of a postmenopausal woman with hyperandrogenism, GnRH agonist treatment significantly reduced testosterone levels, suggesting the androgen excess was ovarian in origin and indicating the potential of using GnRH agonists as a conservative treatment option when surgery is not feasible.

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

This study found that progesterone pretreatment in rats potentiated the effect of ethanol on mesocortical dopamine levels, suggesting an influence of neuroactive steroids on ethanol's action.

This study found that finasteride significantly reduced hirsutism in women with idiopathic hirsutism or polycystic ovary syndrome over six months, suggesting its potential effectiveness for this condition.

This review discusses how the HSD3B1(1245C) genotype may impact androgen physiology and the progression of castration-resistant prostate cancer, and does not report new experimental results.

This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.

This study found that diphlorethohydroxycarmalol significantly increased prostaglandin $E_2$ synthesis in HaCaT human keratinocytes by upregulating COX-1 and COX-2 expression, suggesting potential benefits from elevated $PGE_2$ production.

This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.

This study found that prostaglandin D2 promotes androgen receptor and AKT signaling in human dermal papilla cells through the DP2 receptor, potentially contributing to androgenetic alopecia.

This study developed a validated method using UPLC-MS/MS to analyze 37 hormones in human hair, enabling broader hormonal profiling for identifying endocrine disorders.

This study assessed various androgens' diagnostic effectiveness for hyperandrogenaemia in PCOS using ROC curve analysis, but it reports no specific new results.

This review discusses the pathophysiology, molecular genetics, and management of non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, with no new clinical findings reported.

In this study, treatments combining betamethasone and anovulatory steroids significantly reduced testosterone production in women with hirsutism, with many reporting improved hirsutism and acne, although clinical benefit did not consistently correlate with testosterone reduction.

This study observed that male human hair follicles metabolized dehydroepiandrosterone (DHA) more intensively than skin did and found altered DHA metabolism in follicles from balding individuals.

This study found that brothers of women with PCOS exhibit elevated DHEAS levels, indicating a potential familial genetic trait, but did not show increased rates of premature balding.

This study found that spironolactone significantly reduced hirsutism scores in women with idiopathic hirsutism compared to finasteride and cyproterone acetate but showed no significant difference among women with PCOS compared to flutamide and finasteride, and it was well tolerated overall.

This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.