research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
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research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Co-Editors’ Messages
A man had hiccups for several days after a hair transplant, likely due to medication or nerve irritation, but they stopped on their own.
research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis
Tofacitinib may help treat severe hair loss, but more research is needed.
research Managing Scalp Ringworm in Children
New treatments for children's scalp ringworm are recommended based on recent data.
research Development and Characterization of Poly(Lactic-Co-Glycolic Acid) Nanoparticles With Finasteride and In Vivo Evaluation of Their Efficacy in Hair Growth
Finasteride-loaded nanoparticles were successfully created for potential improved hair growth treatment.
research Ethanolic Extract of Ganoderma Lucidum for Androgenic Alopecia Treatment in Testosterone-Induced Bald Rats
Ganoderma lucidum extract promotes hair growth in bald rats, with higher doses producing better results, similar to the effects of Minoxidil 2%.
research Emulsion Formulation Assays Based on Natural Substances Stimulating Hair Growth and Evaluation of Its Biological Activity
A stable emulsion made with plant extracts and oils was effective in stimulating hair growth.
research Variability of Retail Pricing of Generic Urologic Medications in a Major US Metropolitan Area
Generic urologic medication prices vary by pharmacy type, not by location or income level.
research The Ability of Melatonin to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata
Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
research Comparison of the Therapeutic Effect Between Ethanolic Extract of Physalis Peruviana Fruit, Finasteride, and Terazosine on Benign Prostatic Hyperplasia Induced in Rats
Physalis peruviana extract is more effective in treating benign prostatic hyperplasia in rats than finasteride and terazosine.
research Randomized Comparison of Topical Betamethasone Valerate Foam, Intralesional Triamcinolone Acetonide, and Tacrolimus Ointment in Management of Localized Alopecia Areata
Intralesional triamcinolone acetonide is the most effective treatment for localized alopecia areata.
research Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
research Co-Administration of 5α-Reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.
research Methotrexate-Associated Lymphoproliferative Disorder: Sequential Development of Angioimmunoblastic T-Cell Lymphoma-Like Lymphoproliferation in the Lymph Nodes and Diffuse Large B-Cell Lymphoma in the Skin in the Same Patient
Stopping methotrexate might reverse lymphoma-like conditions in some patients.
research Efficacy of Antihistamines in Combination with Topical Corticosteroid and Superficial Cryotherapy for Treatment of Alopecia Areata: A Retrospective Cohort Study
Adding antihistamines to topical corticosteroid and cryotherapy may improve hair regrowth in alopecia areata patients.
research Cronkhite-Canada Syndrome Associated with Colon Cancer Metastatic to Liver
A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.
research Lugol's Solution-Induced Painless Thyroiditis
Lugol's solution can cause thyroid problems if used long-term for non-approved reasons.
research The Effects of Benzodiazepines on Hormones in Women with Idiopathic Hirsutism
Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.
research A Patient With Insulin-Dependent Diabetes Mellitus 1 Year After Being Diagnosed With Membranous Glomerulonephritis
A 9-year-old girl developed type 1 diabetes and alopecia after being treated for a rare kidney disease.
research Comparative Efficacy and Safety of JAK Inhibitors in the Treatment of Moderate-to-Severe Alopecia Areata: A Systematic Review and Network Meta-Analysis
Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.
research A Rare Case of Orthokeratotic Hyperkeratosis in a Kid Induced by Malassezial Dermatitis
A young goat with skin issues improved with medication and supplements.
research Therapeutic Management of Generalized Canine Demodicosis With Secondary Bacterial and Yeast Infections: A Case Report
The dog fully recovered one month after treatment.
research Isoniazid-Induced Alopecia: A Rare Entity
Isoniazid can rarely cause hair loss, which is reversible after stopping the drug.
research The Treatment of Opioid Addiction Leading to Secondary Adrenal Insufficiency
Long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency.
research Alopecia Areata: Case Study of a 55-Year-Old Malaysian Chinese Man Treated at Dr. Inder Clinic
Early-stage Alopecia Areata was effectively treated in less than six months.
research Step-By-Step Hair Transplantation Surgery: FUE Method
The document is a guide for practitioners to successfully perform hair transplants using the FUE method.
research Giant Bilateral Myelolipomas in a Patient with Congenital Adrenal Hyperplasia
A patient with untreated congenital adrenal hyperplasia had large benign tumors in her adrenal glands removed, improving her symptoms.
research The Polycystic Ovary Syndrome: A Position Statement from the European Society of Endocrinology
The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
research JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.