TLDR Combining cyclosporine A and ketoconazole can effectively treat anal furunculosis in dogs, with some experiencing recurrences and mild side effects.
In a study from 2004, 19 dogs with anal furunculosis were treated with a combination of cyclosporine A and ketoconazole, resulting in complete resolution of lesions in three to 10 weeks. However, 36.8% of the dogs experienced recurrences with remission periods ranging from one to six months. Some dogs exhibited adverse effects such as excessive hair loss, lethargy, vomiting, and decreased appetite, but these were not considered serious. The combined treatment was found to be as effective, if not more so, than surgical options and offered a cost saving of approximately 70% compared to using cyclosporine alone.
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