An Umbrella Review of the Use of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia

This study found that topical finasteride significantly increased hair count in men with androgenetic alopecia compared to placebo while maintaining similar efficacy to oral finasteride but with lower systemic exposure and a reduced impact on serum DHT levels, potentially minimizing sexual side effects.

This review highlights platelet-rich plasma as a promising nonsurgical treatment for female pattern hair loss, but it reports no new clinical results.

This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.

This article reviews the use of platelet-rich plasma for skin rejuvenation and hair regrowth, noting positive outcomes despite variability in preparation and a lack of standardized protocols.

In this study, PRP increased hair density in areas treated for androgenetic alopecia, but there was no significant difference when compared to placebo-treated areas.

This systematic review study found that platelet-rich plasma treatment may improve hair density and diameter in women with androgenetic alopecia, although the findings are limited by the small sample sizes and pilot nature of the included studies.

This article reviews major uses of platelet-rich plasma in treating various hair disorders, including both non-cicatricial and cicatricial alopecia, but reports no new results.

This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.

This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.

This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.

This review evaluates the use of platelet-rich plasma in dermatology, highlighting favorable outcomes in several areas, especially androgenetic alopecia, despite a lack of large randomized controlled trials and consistency in protocols.

This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.

This review covers nonsteroid-based therapies for alopecia areata, finding potential in PRP, UVR, and laser treatments, but highlights a lack of high-quality evidence for their efficacy.

This research review found that platelet-rich plasma treatment generally produced successful hair regrowth in both androgenetic alopecia and alopecia areata, despite study differences that limited direct statistical comparison.

Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.

This review highlights new treatment options for hair restoration, including platelet-rich plasma and stem cell therapy, which have shown efficacy in increasing hair count and density for androgenetic alopecia and alopecia areata, but presents no original clinical data.

This study's meta-analysis reported that PRP injections significantly increased hair density compared to baseline and placebo in androgenetic alopecia patients, supporting its use as a beneficial treatment.

This review found insufficient evidence to support the use of platelet rich plasma procedures for treating androgenetic alopecia.

This review found that three monthly PRP injections improved hair density in patients with androgenetic alopecia compared to placebo, but more rigorous studies are needed for broader dermatological applications.

This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.

This review analyzed clinical trial protocols for platelet-rich plasma preparation in hair loss treatment, finding inconsistent and insufficient reporting that complicates comparison and efficacy determination.

This review discusses the use of platelet-rich plasma for facial rejuvenation, acne scarring, and androgenic alopecia and reports positive outcomes but emphasizes the need for standardized preparation and application methods.

This meta-analysis found that treating male androgenetic alopecia with 5α-reductase inhibitors increases the risk of sexual dysfunction, with a statistically significant risk for finasteride but not for dutasteride.

This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.

This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.

This meta-analysis suggests that local injection of platelet-rich plasma for androgenic alopecia is associated with an increased number of hairs and some increase in hair thickness, though larger studies are needed for confirmation.

This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.

This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.

This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.

This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.

This study found that platelet-rich plasma was not effective in treating androgenetic alopecia in men with grade 4–6 hair loss.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

This review discusses the use of platelet-rich plasma for pattern hair loss treatment and examines existing clinical studies without presenting new clinical results.

This analysis suggests that platelet-rich plasma therapy may be promising for treating androgenetic alopecia, but further controlled trials with standardized measures are needed to confirm its efficacy.

This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.

This review discusses the cosmetic applications of platelet-rich plasma in dermatology, highlighting its potential benefits and the need for more controlled studies.

This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.

This study found that people with androgenic alopecia, particularly women, are more prone to anxiety and depression, often adopting avoidant coping strategies, which are linked to emotional and psychological impacts rather than clinical severity.

This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.