TLDR Saw palmetto extracts might help treat male hair loss and need more research.
The document discusses the role of the enzyme 5-α-reductase in male androgenetic alopecia (MAGA), which disrupts hair follicle nourishment and accelerates the transition from the anagen to the catagen phase of hair growth by converting testosterone into dihydrotestosterone (DHT). The study suggests that inhibitors can target this enzyme and proposes further research into the effects of saw palmetto extracts, specifically stigmasterol and β-sitosterol, due to their inhibitory activity. It also advocates for investigating the impact of saw palmetto extract on the hair growth cycle, hair follicle life cycle, various growth factors and angiogenesis, immune system activity, and oxidative stress.View this study on annales.sum.edu.pl →
Hair loss is more common in male Chinese college freshmen, and it's linked with rosacea but doesn't affect their quality of life.
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
DHT stops hair regrowth in mice, similar to human hair loss.
In Spain, dermatologists most commonly prescribe topical minoxidil and oral finasteride for male hair loss, and topical minoxidil and oral contraceptives for female hair loss. The use of oral dutasteride and oral minoxidil has significantly increased over the past three years.
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.
Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
No cure for female pattern hair loss, but various effective treatments exist.
Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.
People with hair loss have different hormone levels, and these hormones can affect hair growth.
DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.