Androgenic Hormone Profile in Patients with Androgenetic Alopecia

December 2015 in “ Vestnik dermatologii i venerologii ”

I. N. Konrakhina, И Н Кондрахина, A. N. Mareeva, А Н Мареева, P. A. Kalinina, П. А. Калинина, M. G. Abuladze, М. Г. Абуладзе

androgenetic alopecia testosterone dihydrotestosterone dehydroepiandrosterone sulfate sex hormone-binding globulin androgens hair follicles 5-alpha reductase DHT SHBG DHEA-S

TLDR People with hair loss have different hormone levels, and these hormones can affect hair growth.

The document from 7 years ago, "Androgenic hormone profile in patients with androgenetic alopecia," presented the results of various studies on the levels of testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, sex hormone-binding globulin, and other components of the androgen hormone profile in males with androgenetic alopecia. The research also explored the effects of androgens on hair follicles and the role of 5-alpha reductase in the conversion of androgens.

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Research cited in this study

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research Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia

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DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

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Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

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Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old

research Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old

18 citations, March 2008 in “British Journal of Dermatology”

Finasteride works better for hair loss in patients 26 or younger.

research Male Androgenetic Alopecia: Medical and Surgical Treatments

9 citations, February 2005 in “The Journal of Men's Health & Gender”

Finasteride effectively treats male hair loss, increasing length and thickness.

research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia

32 citations, August 1999 in “Journal of Investigative Dermatology”

Early onset hair loss linked to genetics and androgen levels.

Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques

research Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques

18 citations, January 1998 in “Endocrine”

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations, September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Relations Between Sex Hormone Levels and Characteristics of Hair and Skin in Healthy Young Men

18 citations, May 1992 in “American Journal of Biological Anthropology”

Higher androgen levels do not cause baldness in men.

research Hormonal Parameters in Androgenetic Hair Loss in Males

21 citations, January 1991 in “Dermatology”

Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.

research Sex Hormone-Binding Globulin and Saliva Testosterone Levels in Men with Androgenetic Alopecia

29 citations, September 1983 in “British Journal of Dermatology”

Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 840 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 62 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 4 months ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community When are we getting a cure to hair loss?

in Chat 1 year ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 145 upvotes 5 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

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