Androgenic Hormone Profile in Patients with Androgenetic Alopecia

December 2015 in “ Vestnik dermatologii i venerologii ”

I. N. Konrakhina, И Н Кондрахина, A. N. Mareeva, А Н Мареева, P. A. Kalinina, П. А. Калинина, M. G. Abuladze, М. Г. Абуладзе

androgenetic alopecia testosterone dihydrotestosterone dehydroepiandrosterone sulfate sex hormone-binding globulin androgens hair follicles 5-alpha reductase DHT SHBG DHEA-S

TLDR People with hair loss have different hormone levels, and these hormones can affect hair growth.

The document from 7 years ago, "Androgenic hormone profile in patients with androgenetic alopecia," presented the results of various studies on the levels of testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, sex hormone-binding globulin, and other components of the androgen hormone profile in males with androgenetic alopecia. The research also explored the effects of androgens on hair follicles and the role of 5-alpha reductase in the conversion of androgens.

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Research cited in this study

12 / 12 results

research Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia

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DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

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Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

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Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old

research Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old

18 citations, March 2008 in “British Journal of Dermatology”

Finasteride works better for hair loss in patients 26 or younger.

research Male Androgenetic Alopecia: Medical and Surgical Treatments

9 citations, February 2005 in “The Journal of Men's Health & Gender”

Finasteride effectively treats male hair loss, increasing length and thickness.

research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia

32 citations, August 1999 in “Journal of Investigative Dermatology”

Early onset hair loss linked to genetics and androgen levels.

Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques

research Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques

18 citations, January 1998 in “Endocrine”

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations, September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Relations Between Sex Hormone Levels and Characteristics of Hair and Skin in Healthy Young Men

18 citations, May 1992 in “American Journal of Biological Anthropology”

Higher androgen levels do not cause baldness in men.

research Hormonal Parameters in Androgenetic Hair Loss in Males

21 citations, January 1991 in “Dermatology”

Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.

research Sex Hormone-Binding Globulin and Saliva Testosterone Levels in Men with Androgenetic Alopecia

29 citations, September 1983 in “British Journal of Dermatology”

Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

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Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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