TGF-β Family Signaling in Stem Cells

    August 2012 in “ Biochimica et Biophysica Acta (BBA) - General Subjects ”
    Masayo Sakaki-Yumoto, Yoko Katsuno, Rik Derynck
    Studysummary This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
    2. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011
    3. Tracking Adult Stem Cells EMBO Reports · 2011
    4. Stem Cells and the Niche: A Dynamic Duo Cell Stem Cell · 2010
    5. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    6. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006
    7. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    8. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    9. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001
    10. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000