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GlossaryAdult Stem Cells (Somatic Stem Cells)

undifferentiated cells in adults that regenerate specific tissues

Adult stem cells, also known as somatic stem cells, are undifferentiated cells found throughout the body after development. They have the ability to self-renew and differentiate into various specialized cell types of the tissue or organ they reside in, playing a crucial role in tissue repair and regeneration. Unlike embryonic stem cells, adult stem cells are limited in their differentiation potential but are less likely to cause ethical concerns or immune rejection when used in therapies.

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research Somatic Stem Cell Heterogeneity: Diversity in the Blood, Skin, and Intestinal Stem Cell Compartments

137 citations, April 2015 in “Nature Reviews Molecular Cell Biology”

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

research TGF-β Family Signaling in Stem Cells

132 citations, August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

research Clonal Analysis of Stem Cells in Differentiation and Disease

11 citations, July 2016 in “Current Opinion in Cell Biology”

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

research Human Epidermal Neural Crest Stem Cells as Candidates for Cell-Based Therapies, Disease Modeling, and Drug Discovery

13 citations, September 2014 in “Birth defects research”

Human epidermal neural crest stem cells could be used for therapies, drug discovery, and disease modeling.

research The Stem Cell Niche

January 2019 in “Elsevier eBooks”

Understanding stem cell environments is key to developing treatments for various diseases and injuries.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 month ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community What should we lookout for in the near future for hairloss?

in Research/Science 17 upvotes 1 year ago

The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 89 upvotes 3 months ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.