WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

    June 2017 in “ Nature Communications ”
    Mingang Xu, Jeremy Horrell, Melinda Snitow … Sarah E. Millar
    Studysummary This study identified WNT10A as crucial for adult epithelial cell proliferation and differentiation, suggesting β-catenin pathway activation may help address regenerative defects in WNT10A mutation patients.
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